KEGG   ENZYME: 1.1.1.9Help
Entry
EC 1.1.1.9                  Enzyme                                 
Name D-xylulose reductase;
NAD+-dependent xylitol dehydrogenase;
xylitol dehydrogenase;
erythritol dehydrogenase;
2,3-cis-polyol(DPN) dehydrogenase (C3-5);
pentitol-DPN dehydrogenase;
xylitol-2-dehydrogenase
Class Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname xylitol:NAD+ 2-oxidoreductase (D-xylulose-forming)
Reaction(IUBMB) xylitol + NAD+ = D-xylulose + NADH + H+ [RN:R01896]
Reaction(KEGG) R01896
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Substrate xylitol [CPD:C00379];
NAD+ [CPD:C00003]
Product D-xylulose [CPD:C00310];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment Also acts as an L-erythrulose reductase.
Pathway PATH: ec00040  Pentose and glucuronate interconversions
PATH: ec01100  Metabolic pathways
Orthology KO: K05351  D-xylulose reductase
Genes SCE: YLR070C(XYL2)
PIC: PICST_86924(XYL2)
AFM: AFUA_1G04820
ETA: ETA_16670
PLU: plu1960
PAY: PAU_02204(ydjJ)
SGL: SG0610
CSA: Csal_2609
BMA: BMAA1076
BMV: BMASAVP1_0068
BML: BMA10229_0351
BMN: BMA10247_A1235
BPS: BPSS1235
BPM: BURPS1710b_A0234
BPL: BURPS1106A_A1653
BPD: BURPS668_A1742
BTE: BTH_II1176
BUR: Bcep18194_B3068
BCN: Bcen_5063
BCH: Bcen2424_5797
MLO: mlr4915
SME: SMc01992
ATU: Atu4318
ATC: AGR_L_1091
RET: RHE_PE00268(ype00129)
RLE: pRL110382
RDE: RD1_3623(xdh)
PDE: Pden_2163
DSH: Dshi_0551(xylD)
GDI: GDI_3142
RRU: Rru_A0252
BAD: BAD_0317
Taxonomy
Structures PDB: 1ZEM  
Reference
  Authors
  Title
  Journal
  Organism
 1  [PMID:13692998]
CHIANG C, KNIGHT SG.
A new pathway of pentose metabolism.
Biochem. Biophys. Res. Commun. 3 (1960) 554-9.
Penicillium chrysogenum [GN:pcs]
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:13654257]
HICKMAN J, ASHWELL G.
A sensitive and stereospecific enzymatic assay for xylulose.
J. Biol. Chem. 234 (1959) 758-61.
Cavia porcellus
Reference
  Authors
  Title
  Journal
  Organism
 3  [PMID:13789254]
JAKOBY WB, FREDERICKS J.
Erythritol dehydrogenase from Aerobacter aerogenes.
Biochim. Biophys. Acta. 48 (1961) 26-32.
Klebsiella pneumoniae [GN:kpn]
Other DBs ExplorEnz - The Enzyme Database: 1.1.1.9
IUBMB Enzyme Nomenclature: 1.1.1.9
ExPASy - ENZYME nomenclature database: 1.1.1.9
BRENDA, the Enzyme Database: 1.1.1.9
CAS: 9028-16-4
DBGET integrated database retrieval system