| Entry |
|
|---|
| Name |
oxaloglycolate reductase (decarboxylating) |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
D-glycerate:NAD(P)+ oxidoreductase (carboxylating) |
|---|
| Reaction(IUBMB) |
D-glycerate + NAD(P)+ + CO2 = 2-hydroxy-3-oxosuccinate + NAD(P)H + 2
H+ [RN:R01749 R01750] |
|---|
| Reaction(KEGG) |
R01749 R01750
 |
|---|
| Substrate |
D-glycerate [CPD:C00258];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
CO2 [CPD:C00011] |
|---|
| Product |
2-hydroxy-3-oxosuccinate [CPD:C03459];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
Also reduces hydroxypyruvate to D-glycerate and glyoxylate to
glycolate. |
|---|
| Pathway |
PATH: ec00630 Glyoxylate and dicarboxylate metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4385076]
Kohn LD, Jakoby WB.
Tartaric acid metabolism. VI. Crystalline oxaloglycolate reductive
decarboxylase.
J. Biol. Chem. 243 (1968) 2486-93.
Pseudomonas putida |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.92
IUBMB Enzyme Nomenclature: 1.1.1.92
ExPASy - ENZYME nomenclature database: 1.1.1.92
BRENDA, the Enzyme Database: 1.1.1.92
CAS: 37250-28-5 |
|---|
