KEGG   ENZYME: 1.1.1.95Help
Entry
EC 1.1.1.95                 Enzyme                                 
Name phosphoglycerate dehydrogenase;
D-3-phosphoglycerate:NAD+ oxidoreductase;
alpha-phosphoglycerate dehydrogenase;
3-phosphoglycerate dehydrogenase;
3-phosphoglyceric acid dehydrogenase;
D-3-phosphoglycerate dehydrogenase;
glycerate 3-phosphate dehydrogenase;
glycerate-1,3-phosphate dehydrogenase;
phosphoglycerate oxidoreductase;
phosphoglyceric acid dehydrogenase;
SerA;
3-phosphoglycerate:NAD+ 2-oxidoreductase;
SerA 3PG dehydrogenase;
3PHP reductase;
alphaKG reductase;
D- and L-HGA
Class Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname 3-phospho-D-glycerate:NAD+ 2-oxidoreductase
Reaction(IUBMB) (1) 3-phospho-D-glycerate + NAD+ = 3-phosphonooxypyruvate + NADH +
H+ [RN:R01513];
(2) 2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+
[RN:R08198]
Reaction(KEGG) R01513 R08198
Show
Substrate 3-phospho-D-glycerate [CPD:C00197];
NAD+ [CPD:C00003];
2-hydroxyglutarate [CPD:C02630]
Product 3-phosphonooxypyruvate [CPD:C03232];
NADH [CPD:C00004];
H+ [CPD:C00080];
2-oxoglutarate [CPD:C00026]
Comment This enzyme catalyses the first committed step in the phosphoserine
pathway of serine biosynthesis in Escherichia coli [2,3]. Reaction
(1) occurs predominantly in the reverse direction and is inhibited
by serine and glycine. The enzyme is unusual in that it also acts as
a D- and L-2-hydroxyglutarate dehydrogenase (with the D-form being
the better substrate) and as a 2-oxoglutarate reductase [3]. It has
been postulated [3] that the cellular 2-oxoglutarate concentration
may regulate serine biosynthesis and one-carbon metabolism directly
by modulating the activity of this enzyme.
Pathway PATH: ec00260  Glycine, serine and threonine metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00058  D-3-phosphoglycerate dehydrogenase
Genes HSA: 26227(PHGDH)
PTR: 739534(PHGDH)
MCC: 713480(PHGDH)
MMU: 236539(Phgdh)
RNO: 58835(Phgdh)
CFA: 607890
BTA: 505103(PHGDH)
SSC: 100144529(CH242-38B5.2)
ECB: 100059940
MDO: 100012806
OAA: 100092875
GGA: 424381(PHGDH)
XLA: 100037051
XTR: 548683
DRE: 321928(phgdh)
CIN: 100186739
SPU: 590971
DME: Dmel_CG6287
DPO: Dpse_GA19489
DAN: Dana_GF15130
AGA: AgaP_AGAP008849
AAG: AaeL_AAEL005336
AME: 725967
TCA: 663218
API: 100165735(Acypi006664)
CEL: C31C9.2
CBR: CBG20736
BMY: Bm1_57055
NVE: NEMVE_v1g170150
TAD: TRIADDRAFT_37449
ATH: AT1G17745(PGDH) AT3G19480 AT4G34200(EDA9)
OSA: 4337230(Os04g0650800) 4341713(Os06g0655100)
PPP: PHYPADRAFT_131174
CRE: CHLREDRAFT_78757(PGD1)
OLU: OSTLU_13344 OSTLU_39000
CME: CMC149C
SCE: YER081W(SER3) YIL074C(SER33)
AGO: AGOS_ACL032C
KLA: KLLA0C09306g
DHA: DEHA0B11198g
PIC: PICST_87754(SER3)
VPO: Kpol_387p9 Kpol_411p5
CAL: CaO19.12728(SER3)
CGR: CAGL0M12837g
YLI: YALI0F09966g
SPO: SPCC364.07
NCR: NCU01439
PAN: PODANSg2909 PODANSg8350
MGR: MGG_07207 MGG_11794
FGR: FG07468.1 FG09483.1
ANI: AN8866.2
AFM: AFUA_1G14400 AFUA_2G04490 AFUA_4G11840 AFUA_5G05500
AOR: AO090009000711
ANG: An17g02330
NFI: NFIA_037560 NFIA_081250
SSL: SS1G_00194
BFU: BC1G_04899 BC1G_06095
CNE: CNA07520
CNB: CNBA7340
LBC: LACBIDRAFT_291447
UMA: UM01233.1
MGL: MGL_1179
MBR: MONBRDRAFT_37889
DDI: DDB_0230052(serA)
EHI: EHI_060860
LMA: LmjF03.0030
TVA: TVAG_154750
ECO: b2913(serA)
ECJ: JW2880(serA)
ECD: ECDH10B_3088(serA)
EBW: BWG_2637(serA)
ECE: Z4251(serA)
ECS: ECs3784
ECF: ECH74115_4208(serA)
ETW: ECSP_3880(serA)
ECG: E2348C_3081 E2348C_3164(serA)
ECC: c3405 c3494(serA)
ECI: UTI89_C3212 UTI89_C3299(serA)
ECP: ECP_2824 ECP_2905
ECV: APECO1_3616(serA) APECO1_3693
ECW: EcE24377A_3240(serA)
ECX: EcHS_A3071(serA)
ECM: EcSMS35_2958 EcSMS35_3046(serA)
ECY: ECSE_3175
ECL: EcolC_0797
ECK: EC55989_3200(serA)
ECQ: ECED1_3268 ECED1_3371(serA)
ECR: ECIAI1_3032(serA)
ECT: ECIAI39_3328(serA)
ECZ: ECS88_3107 ECS88_3192(serA)
EUM: ECUMN_3254(serA)
ELF: LF82_2115(serA) LF82_p447
EBL: B21_02707(serA)
EBD: ECBD_0825
EBR: ECB_02744(serA)
EFE: EFER_2850(serA)
STY: STY3218(serA)
STT: t2980(serA)
SPT: SPA2933(serA)
SEK: SSPA2732
SPQ: SPAB_03816
SEI: SPC_3123(serA)
SEC: SC3003(serA)
SEH: SeHA_C3297(serA)
SEE: SNSL254_A3300(serA)
SEW: SeSA_A3235(serA)
SEA: SeAg_B3223(serA)
SED: SeD_A3402(serA)
SEG: SG2957(serA)
SET: SEN2905(serA)
SES: SARI_04588
STM: STM3062(serA)
YPE: YPO0914(serA) YPO1288
YPK: y2896 y3301(serA)
YPM: YP_1303(serA1) YP_3611(serA2)
YPA: YPA_0353 YPA_1004
YPN: YPN_2690 YPN_3113
YPG: YpAngola_A3823(serA)
YPP: YPDSF_0599 YPDSF_2408
YPS: YPTB1320 YPTB3189(serA)
YPI: YpsIP31758_0856(serA)
YPY: YPK_0859
YPB: YPTS_3321
YEN: YE2604 YE3400(serA)
SFL: SF2898(serA)
SFX: S3098(serA)
SFV: SFV_2960(serA)
SSN: SSON_3065(serA)
SBO: SBO_2700 SBO_3080(serA)
SBC: SbBS512_E3053 SbBS512_E3333(serA)
SDY: SDY_3169(serA)
ECA: ECA3905(serA)
ETA: ETA_28070(serA)
PLU: plu3605(serA)
PAY: PAU_01152(serA)
SGL: SG2009
ENT: Ent638_3332
ESA: ESA_00416
CTU: Ctu_34620(serA)
KPN: KPN_00636 KPN_03348(serA)
KPE: KPK_0752(serA) KPK_2753(gyaR) KPK_3939
KPU: KP1_1587 KP1_4635(serA)
CKO: CKO_04278
SPE: Spro_3923
PMR: PMI2031(serA)
HIN: HI0465(serA)
HIT: NTHI0596(serA)
HIP: CGSHiEE_00665
HIQ: CGSHiGG_05565
HAP: HAPS_1043(serA)
HSO: HS_0122(serA)
HSM: HSM_2007
PMU: PM1671(serA)
MSU: MS0068(serA) MS1743(serA)
APL: APL_1452(serA)
APJ: APJL_1474(serA)
APA: APP7_1457
ASU: Asuc_1869
AAP: NT05HA_2355
AAT: D11S_1510
XFA: XF2206
XFT: PD1255(serA)
XFM: Xfasm12_1407
XFN: XfasM23_1340
XCC: XCC0020(serA) XCC1825(serA)
XCB: XC_0020 XC_2364
XCA: xccb100_0022(serA2) xccb100_2112(serA1)
XCV: XCV0023(serA) XCV1890(serA)
XAC: XAC0022(serA) XAC1844(serA)
XOO: XOO2143(serA) XOO4585(serA)
XOM: XOO_2012 XOO_4321
XOP: PXO_03548
SML: Smlt2195(serA)
VCH: VC2481 VCA0630
VCO: VC0395_0573 VC0395_A2057(serA)
VCJ: VCD_000692
VVU: VV1_1546 VV2_0975
VVY: VV2851 VVA1466
VPA: VP2593
VHA: VIBHAR_03556
VFI: VF_2106(serA)
VFM: VFMJ11_2211
PPR: PBPRA3123 PBPRA3124
PAE: PA0316(serA)
PAU: PA14_04110(serA)
PAP: PSPA7_0409(serA)
PPU: PP_2533 PP_5155(serA)
PPF: Pput_5062
PPG: PputGB1_5208
PPW: PputW619_0310
PST: PSPTO_5294(serA)
PSB: Psyr_4852
PSP: PSPPH_4885(serA)
PFL: PFL_5911
PFO: Pfl01_2987 Pfl01_5387
PEN: PSEEN5248(serA)
PMY: Pmen_4232
PSA: PST_0398(serA)
CJA: CJA_0232
PAR: Psyc_0369(serA)
PCR: Pcryo_0410
PRW: PsycPRwf_0569
ACI: ACIAD3302(serA)
ACB: A1S_3152
ABM: ABSDF0338(serA)
ABY: ABAYE0332(serA)
ABC: ACICU_03352
SON: SO_0862(serA)
SDN: Sden_3097
SFR: Sfri_0558
SAZ: Sama_2949
SBL: Sbal_3502
SBM: Shew185_0838
SBN: Sbal195_0873
SLO: Shew_3196
SPC: Sputcn32_3139
SSE: Ssed_3947
SPL: Spea_0631
SHE: Shewmr4_0718
SHM: Shewmr7_3304
SHN: Shewana3_3416
SHW: Sputw3181_0804
SHL: Shal_0723
SWD: Swoo_3889
ILO: IL2104(serA)
CPS: CPS_1544(serA)
PHA: PSHAa0666(serA)
PAT: Patl_1156
SDE: Sde_1333 Sde_3388
MAQ: Maqu_2819
AMC: MADE_03208
PIN: Ping_0600
CBU: CBU_1732
LPN: lpg0242(serA)
LPF: lpl0296
LPP: lpp0312
FTU: FTT_1230(serA)
FTF: FTF1230(serA)
FTL: FTL_0714
FTH: FTH_0716(serA)
TCX: Tcr_0627
NOC: Noc_0173
AEH: Mlg_0925
HHA: Hhal_0569
HCH: HCH_01646(serA)
CSA: Csal_0096 Csal_1770
ABO: ABO_0068(serA)
MMW: Mmwyl1_1580 Mmwyl1_4310
AHA: AHA_2731 AHA_3354
ASA: ASA_0954(serA) ASA_1641(serA)
AFE: Lferr_1018
AFR: AFE_0896(serA)
RMA: Rmag_0627
VOK: COSY_0580(serA)
RSO: RSc0016(serA1) RSp0505(serA2)
RPI: Rpic_3740 Rpic_3984
RPF: Rpic12D_3417 Rpic12D_4097
REU: Reut_A3421 Reut_B3530 Reut_B4615 Reut_B4747 Reut_C5898
REH: H16_A3712(serA1) H16_B0347(serA2) H16_B0824(serA4)
     H16_B0841(serA5) H16_B1819(serA6)
RME: Rmet_3578 Rmet_4234 Rmet_4537
CTI: RALTA_B0655(serA1)
BMA: BMA0137
BMV: BMASAVP1_A2813
BML: BMA10229_A2269
BMN: BMA10247_2346
BPS: BPSL0116 BPSL1250(serA)
BPM: BURPS1710b_0341(serA1) BURPS1710b_1481
BPL: BURPS1106A_0151(gyaR) BURPS1106A_1345(serA)
BPD: BURPS668_0143 BURPS668_1338(serA)
BTE: BTH_I0123 BTH_I2885(serA) BTH_II0982
BVI: Bcep1808_3291
BUR: Bcep18194_A3727 Bcep18194_A6483 Bcep18194_B0500 Bcep18194_B0965
     Bcep18194_B1312 Bcep18194_C7658
BCN: Bcen_2519 Bcen_3835 Bcen_5465
BCH: Bcen2424_3132 Bcen2424_4533 Bcen2424_5397
BCM: Bcenmc03_3148
BAM: Bamb_3187
BMU: Bmul_4705
BXE: Bxe_A2676 Bxe_B1744 Bxe_B1896 Bxe_B2128
BPE: BP0155(serA)
BPA: BPP2132 BPP4001(serA)
BBR: BB1529 BB4474(serA) BB4731
RFR: Rfer_1867 Rfer_2996
POL: Bpro_2956 Bpro_4572 Bpro_5117
PNA: Pnap_1854 Pnap_1916
AAV: Aave_3158 Aave_3649
AJS: Ajs_0863 Ajs_1926
VEI: Veis_0891 Veis_1307 Veis_1427 Veis_2017 Veis_3989 Veis_4913
DAC: Daci_0347 Daci_3541 Daci_4276
DIA: Dtpsy_0792
MPT: Mpe_A1136 Mpe_A1820
HAR: HEAR3340 HEAR3458(tkrA)
NEU: NE0334 NE1688(serA)
NET: Neut_0433 Neut_1571
NMU: Nmul_A0428 Nmul_A2191
EBA: ebA6869(serA)
AZO: azo3099(serA)
TBD: Tbd_0950
MFA: Mfla_0724
APP: CAP2UW1_2565
HPY: HP0397
HPJ: jhp0984(serA)
HPA: HPAG1_0995
HPP: HPP12_1023(serA)
HHE: HH0135(serA)
HAC: Hac_0455(serA)
WSU: WS1313(serA)
TDN: Suden_0875
CJE: Cj0891c(serA)
CJR: CJE0970(serA)
CJJ: CJJ81176_0900(serA)
CFF: CFF8240_1248(serA)
CCV: CCV52592_0512(serA)
CCO: CCC13826_1569(serA)
ABU: Abu_2048(serA)
NIS: NIS_0664
SUN: SUN_0551
GSU: GSU1198(serA)
GME: Gmet_2378
GUR: Gura_1737 Gura_3860
PCA: Pcar_0417(serA-1) Pcar_3115(serA-2)
PPD: Ppro_0734 Ppro_1699
DVU: DVU0339
DVL: Dvul_2644
DDE: Dde_3689
LIP: LI0671(serA)
BBA: Bd1461(serA) Bd2892(serA)
DPS: DP1709
ADE: Adeh_1262
ACP: A2cp1_2694
AFW: Anae109_2506
ANK: AnaeK_2601
MXA: MXAN_6356(serA)
SAT: SYN_00123
SFU: Sfum_3136 Sfum_3649
PUB: SAR11_1366(serA)
MLO: mll1021 mll3875 mlr3367 mlr7269
MES: Meso_3161
PLA: Plav_2138
SME: SMa1347 SMc00641(serA) SMc01622
SMD: Smed_2618
ATU: Atu3706(serA) Atu5399
ATC: AGR_L_2264 AGR_pAT_578(serA)
RET: RHE_CH03454(serA) RHE_PC00143(ypc00078) RHE_PF00379(ypf00200)
REC: RHECIAT_CH0003693(serA)
RLE: RL3960 pRL100390 pRL120588
RLT: Rleg2_3192
RLG: Rleg_3486
BME: BMEI0349 BMEII0813
BMF: BAB1_1697 BAB2_0783(serA-2)
BMB: BruAb1_1670(serA-1) BruAb2_0769(serA-2)
BMC: BAbS19_I15880
BMS: BR1685(serA-1) BRA0453(serA-2)
BMT: BSUIS_B1160(serA)
BOV: BOV_1629(serA)
BCS: BCAN_A1723(serA)
BMR: BMI_I1706(serA-1)
OAN: Oant_1229 Oant_3104
BJA: bll6549 bll7401(serA) bll7965 blr3173
BRA: BRADO1760(serA) BRADO2535 BRADO3813 BRADO3860 BRADO4794
     BRADO4922 BRADO5741 BRADO5948(serA)
BBT: BBta_1826(serA) BBta_2073(serA) BBta_2880 BBta_3129 BBta_3231
     BBta_4121 BBta_6253
RPA: RPA1744(serA) RPA2975(serA1) RPA4308(serA2)
RPB: RPB_1315 RPB_4226
RPC: RPC_1669 RPC_4106
RPD: RPD_3905 RPD_4078
RPE: RPE_4160
RPT: Rpal_4789
NWI: Nwi_2968
NHA: Nham_1119
OCA: OCAR_7157(serA)
XAU: Xaut_1202
AZC: AZC_0985
MEX: Mext_0213 Mext_0660
MEA: Mex_1p0486(serA)
MDI: METDI0094(serA) METDI0641(serA2)
MET: M446_6394
MPO: Mpop_0639
MCH: Mchl_0672
BID: Bind_1269
MSL: Msil_1760
CCR: CC_3215
CCS: CCNA_03322
CAK: Caul_4467
PZU: PHZ_c3272(serA)
SIL: SPO3355(serA)
SIT: TM1040_3021
RSP: RSP_1352 RSP_3407(serA) RSP_3447
RSH: Rsph17029_0020 Rsph17029_3052 Rsph17029_3092
RSQ: Rsph17025_0010 Rsph17025_2050
JAN: Jann_0261
RDE: RD1_0197(serA) RD1_3633(serA)
PDE: Pden_0814 Pden_3433
DSH: Dshi_1001(serA2) Dshi_3318(serA1)
HNE: HNE_3126(serA)
ZMO: ZMO1685
NAR: Saro_2680
SAL: Sala_0616
SWI: Swit_4685
ELI: ELI_01970
GOX: GOX0065 GOX0218
ACR: Acry_2572 Acry_2650
GDI: GDI_0211 GDI_1473 GDI_1874(serA)
GDJ: Gdia_0098
RRU: Rru_A2456
RCE: RC1_1786(serA)
MAG: amb3193
MGM: Mmc1_1423
BSU: BSU18560(yoaD) BSU23070(serA)
BHA: BH1602
BAN: BA3320
BAR: GBAA3320
BAA: BA_3822
BAT: BAS3078
BAH: BAMEG_1305
BAI: BAA_3355
BCE: BC3248
BCA: BCE_3284
BCZ: BCZK1299(serA) BCZK2968(serA)
BCR: BCAH187_A3293
BCB: BCB4264_A3260
BCU: BCAH820_3298
BCG: BCG9842_B1989
BCQ: BCQ_3074
BCX: BCA_3352
BCY: Bcer98_2085
BTK: BT9727_3022(serA)
BTL: BALH_1270(serA) BALH_2945(serA)
BWE: BcerKBAB4_2986
BLI: BL00647(serA)
BLD: BLi02446(serA)
BCL: ABC0220 ABC1843(serA)
BAY: RBAM_021220(serA)
BPU: BPUM_2039(serA)
OIH: OB2626(serA)
GKA: GK2247
GTN: GTNG_2184
GWC: GWCH70_2197
GYM: GYMC10_2168
GYC: GYMC61_0432
SAU: SA1545(serA)
SAV: SAV1724(serA)
SAM: MW1666(serA)
SAR: SAR1801
SAS: SAS1650
SAC: SACOL1773(serA)
SAB: SAB1582
SAA: SAUSA300_1670(serA)
SAO: SAOUHSC_01833
SAJ: SaurJH9_1779
SAH: SaurJH1_1814
SAE: NWMN_1617(serA)
SEP: SE1401
SER: SERP1288(serA)
SHA: SH1200(serA)
SSP: SSP1039
SCA: Sca_1330(serA)
LMO: lmo2824
LMF: LMOf2365_2815
LIN: lin2956
LWE: lwe2754
LSP: Bsph_0386
ESI: Exig_1690
BBE: BBR47_24220(serA)
PJD: Pjdr2_2370
AAC: Aaci_1231
LLA: L0084(serA)
LLC: LACR_0620
LLM: llmg_0566(serA)
SAG: SAG1566
SAN: gbs1619
SAK: SAK_1584
SMU: SMU.1653(serA)
STC: str1527(serA)
STL: stu1527(serA)
STE: STER_1487
SSA: SSA_1713(serA) SSA_2085
SSU: SSU05_0667
SSV: SSU98_0667
SUB: SUB0447
LPL: lp_0203(serA1) lp_2790(serA3)
LSA: LSA0922(serA)
LSL: LSL_0092(serA)
LME: LEUM_1463
CAC: CAC0015(serA) CAC0089(serA)
CPE: CPE0054(serA)
CPF: CPF_0061
CPR: CPR_0064
CTC: CTC00694
CNO: NT01CX_0728(serA)
CTH: Cthe_3035
CDF: CD0995(serA)
CBO: CBO1127(serA)
CBA: CLB_1164(serA)
CBH: CLC_1176(serA)
CBY: CLM_1283
CBL: CLK_0567(serA)
CBK: CLL_A3438
CBB: CLD_3436(serA)
CBT: CLH_3217
CBF: CLI_1213(serA)
CBE: Cbei_4927
CKL: CKL_0436(serA) CKL_3816
CKR: CKR_3370
AMT: Amet_3604 Amet_4275
STH: STH9
SWO: Swol_0009
DSY: DSY0969 DSY4683
DRM: Dred_0014
DAE: Dtox_4340
PTH: PTH_0012(serA)
DAU: Daud_0012
EEL: EUBELI_00765
TTE: TTE2613(serA2)
CHY: CHY_2698(serA)
MTA: Moth_0020
ADG: Adeg_0010
CSC: Csac_1304
MTU: Rv0728c(serA2) Rv2996c(serA1)
MTC: MT0753 MT3074(serA)
MRA: MRA_0736(serA2) MRA_3025(serA1)
MTF: TBFG_13011
MBO: Mb0749c(serA2) Mb3020c(serA1)
MBB: BCG_0778c(serA2) BCG_3017c(serA1)
MBT: JTY_3012(serA1)
MLE: ML1692(serA)
MPA: MAP3033c(serA) MAP4194c
MAV: MAV_0349 MAV_3847(serA) MAV_4438
MSM: MSMEG_2378(serA)
MUL: MUL_0823(serA2) MUL_1952(serA1)
MVA: Mvan_2128
MGI: Mflv_4234
MAB: MAB_3304c
MMC: Mmcs_1910
MKM: Mkms_1956
MJL: Mjls_1890
MMI: MMAR_1715(serA1)
CGL: NCgl1235(cgl1284)
CGB: cg1451(serA)
CGT: cgR_1362
CEF: CE1379
CDI: DIP1104(serA)
CJK: jk1291(serA)
NFA: nfa42210(serA)
RHA: RHA1_ro02903(serA1) RHA1_ro03298 RHA1_ro04630
     RHA1_ro06489(serA2) RHA1_ro08844(serA3) RHA1_ro08891
RER: RER_24000(serA)
ROP: ROP_65420(serA)
SCO: SCO5515(SC8D9.27)
SMA: SAV_2730(serA) SAV_7481
SGR: SGR_1997
LXX: Lxx13140(serA)
CMI: CMM_1100(serA)
CMS: CMS_1420(serA)
ART: Arth_2536
AAU: AAur_2506(serA) AAur_pTC20110
ACH: Achl_2276
RSA: RSal33209_1046
KRH: KRH_20570(serA)
PAC: PPA1272 PPA2251
NCA: Noca_3385 Noca_3951
TFU: Tfu_0614
FRA: Francci3_3637
FRE: Franean1_1093
FAL: FRAAL5848(serA) FRAAL6376
ACE: Acel_0709
NML: Namu_1471
KRA: Krad_1513
SEN: SACE_4226(serA) SACE_4558(serA) SACE_4605(serA) SACE_5219(serA)
     SACE_6155(serA)
SVI: Svir_08910
STP: Strop_1236
SAQ: Sare_1126
BLO: BL1313(serA)
BAD: BAD_1112(serA)
RXY: Rxyl_0837
LIL: LA1629 LA1911(serA)
LIC: LIC11992(serA)
LBJ: LBJ_1496
LBL: LBL_1720
ABA: Acid345_0115
SUS: Acid_1661 Acid_5922
BTH: BT_1152
BFR: BF2019
BFS: BF2073(serA)
PGI: PG1279
CHU: CHU_0996(serA) CHU_1630(ldhA)
GFO: GFO_0734(serA) GFO_1469(serA) GFO_3512(serA)
FJO: Fjoh_0839 Fjoh_2461
FPS: FP0639(serA)
FBA: FIC_00525
COC: Coch_1659 Coch_1745
FNU: FN0965
AMU: Amuc_0705
RBA: RB10004(serA) RB6248(serA) RB6394
SYN: sll1908(serA)
SYW: SYNW0533(serA)
SYC: syc2486_c(serA)
SYF: Synpcc7942_1501
SYD: Syncc9605_2150
SYE: Syncc9902_0527
SYG: sync_2256(serA)
SYR: SynRCC307_1844(serA)
SYX: SynWH7803_1981(serA)
SYP: SYNPCC7002_A1246(serA)
CYA: CYA_1354(serA)
CYB: CYB_1383(serA)
TEL: tlr0325(serA)
MAR: MAE_50690(serA)
CYT: cce_2134(serA)
CYP: PCC8801_2377
CYC: PCC7424_4778
CYN: Cyan7425_3375
GVI: gvip294(serA)
ANA: alr1890
NPU: Npun_R5218
AVA: Ava_3759
PMA: Pro1436(serA)
PMM: PMM1354(serA)
PMT: PMT1431(serA)
PMN: PMN2A_0926
PMI: PMT9312_1452
PMB: A9601_04421(engA) A9601_15551(serA)
PMC: P9515_15151(serA)
PMF: P9303_05241(serA)
PMG: P9301_15401(serA)
PMH: P9215_15831(serA)
PMJ: P9211_14091(serA)
PME: NATL1_17821(serA)
TER: Tery_4196
AMR: AM1_1274(serA)
CCH: Cag_1377
CPH: Cpha266_1089
DET: DET0599(serA)
DEH: cbdb_A580(serA)
DEB: DehaBAV1_0574
RRS: RoseRS_0271
CAU: Caur_0280
CHL: Chy400_0300
DRA: DR_1291
DGE: Dgeo_0710
TTH: TTC0586 TTC1209
TTJ: TTHA0952
AAE: aq_1905(serA)
HYA: HY04AAS1_0786
SUL: SYO3AOP1_0259
SAF: SULAZ_1703(serA)
PMX: PERMA_0333(serA)
TMA: TM0327 TM1401
TPT: Tpet_0592 Tpet_1382
TRQ: TRQ2_1428
TNA: CTN_1190
TME: Tmel_0112
DTH: DICTH_1665 DICTH_1741(serA)
DTU: Dtur_0039
TYE: THEYE_A0937(serA)
MJA: MJ1018
MFE: Mefer_0636
MVU: Metvu_1427
MMP: MMP1588(serA)
MMQ: MmarC5_1821
MMX: MmarC6_1082
MMZ: MmarC7_0835
MAE: Maeo_0567
MVN: Mevan_0900
MAC: MA0592(serA)
MBA: Mbar_A1431
MMA: MM_1753
MBU: Mbur_2385
MTP: Mthe_1224
MHU: Mhun_3063
MLA: Mlab_1543
MEM: Memar_1850
MBN: Mboo_2164
MPL: Mpal_0439
MTH: MTH970
MST: Msp_1145(serA)
MSI: Msm_0457
MKA: MK0297 MK0319 MK0320(serA)
AFU: AF0813(serA)
HAL: VNG2424G(serA1)
HSL: OE4408F(serA1)
HMA: rrnAC0362(serA4) rrnAC1762(serA2) rrnAC2056(serA3)
     rrnAC2451(serA5) rrnAC2696(serA1)
HWA: HQ1043A(serA) HQ2066A(serA) HQ2909A(serA)
NPH: NP0272A(serA)
HLA: Hlac_2722
PTO: PTO0372
PHO: PH0520
PAB: PAB0514(serA-like) PAB1008
PFU: PF0370 PF1394
TKO: TK0551 TK1966
TON: TON_0569 TON_1463
TGA: TGAM_0320(serA)
RCI: RCIX1538(serA)
SMR: Smar_0554
IHO: Igni_0383
SSO: SSO0905(serA-1) SSO3187(serA-2)
STO: ST0694 ST1218
SAI: Saci_0247 Saci_1368
MSE: Msed_1059 Msed_1283 Msed_1675
PAI: PAE1038 PAE3320
PIS: Pisl_0566
PCL: Pcal_1741
PAS: Pars_1736
CMA: Cmaq_0792
TNE: Tneu_1556
NMR: Nmar_1258
Taxonomy
Structures PDB: 1PSD  1SC6  1WWK  1YBA  1YGY  2EKL  2G76  2P9C  2P9E  2P9G  
     2PA3  3DC2  3DDN  3EVT  3GG9  3K5P  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:4384871]
Sugimoto E, Pizer LI.
The mechanism of end product inhibition of serine biosynthesis. I.
Purification and kinetics of phosphoglycerate dehydrogenase.
J. Biol. Chem. 243 (1968) 2081-9.
Escherichia coli [GN:eco]
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:14086727]
PIZER LI.
THE PATHWAY AND CONTROL OF SERINE BIOSYNTHESIS IN ESCHERICHIA COLI.
J. Biol. Chem. 238 (1963) 3934-44.
Escherichia coli [GN:eco]
Reference
  Authors
  Title


  Journal
  Organism
 3  [PMID:8550422]
Zhao G, Winkler ME.
A novel alpha-ketoglutarate reductase activity of the serA-encoded
3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its
possible implications for human 2-hydroxyglutaric aciduria.
J. Bacteriol. 178 (1996) 232-9.
Escherichia coli [GN:eco]
Reference
  Authors
  Title

  Journal
  Organism
 4  [PMID:7719856]
Schuller DJ, Grant GA, Banaszak LJ.
The allosteric ligand site in the Vmax-type cooperative enzyme
phosphoglycerate dehydrogenase.
Nat. Struct. Biol. 2 (1995) 69-76.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 1.1.1.95
IUBMB Enzyme Nomenclature: 1.1.1.95
ExPASy - ENZYME nomenclature database: 1.1.1.95
BRENDA, the Enzyme Database: 1.1.1.95
CAS: 9075-29-0
DBGET integrated database retrieval system