| Entry |
|
|---|
| Name |
D-lactate dehydrogenase (cytochrome);
lactic acid dehydrogenase;
D-lactate (cytochrome) dehydrogenase;
cytochrome-dependent D-(-)-lactate dehydrogenase;
D-lactate-cytochrome c reductase;
D-(-)-lactic cytochrome c reductase |
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With a cytochrome as acceptor
 |
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| Sysname |
(R)-lactate:ferricytochrome-c 2-oxidoreductase |
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| Reaction(IUBMB) |
(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c
[RN:R00197] |
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| Reaction(KEGG) |
R00197
 |
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| Substrate |
(R)-lactate [CPD:C00256];
ferricytochrome c [CPD:C00125] |
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| Product |
pyruvate [CPD:C00022];
ferrocytochrome c [CPD:C00126] |
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| Cofactor |
FAD [CPD:C00016] |
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| Comment |
A flavoprotein (FAD). |
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| Pathway |
PATH: ec00620 Pyruvate metabolism |
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| Orthology |
KO: K00102 D-lactate dehydrogenase (cytochrome) |
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| Genes |
HSA: 197257(LDHD)
PTR: 454245(LDHD)
MCC: 713589
MMU: 52815(Ldhd)
RNO: 307858(Ldhd)
CFA: 610390(LDHD)
BTA: 510284(LDHD)
ECB: 100055206(LDHD)
MDO: 100023661
TGU: 100227651
DRE: 334208(ldhd)
SPU: 591812
NVE: NEMVE_v1g173328
OLU: OSTLU_46355
SCE: YDL174C(DLD1)
AGO: AGOS_AER321W
KLA: KLLA0F05753g
DHA: DEHA0B10362g DEHA0D09658g DEHA0F07612g
PIC: PICST_31583(DLD3) PICST_52647(DLD4) PICST_86747(DLD1)
PICST_89565(DLD2)
CGR: CAGL0I05148g CAGL0J06314g
YLI: YALI0E03212g
NCR: NCU00904 NCU02179 NCU06441
MGR: MGG_01202 MGG_12830
ANI: AN9066.2
AFM: AFUA_1G00510 AFUA_1G17520 AFUA_3G06820 AFUA_7G02560
AOR: AO090038000632
ANG: An11g09520 An12g00020 An12g06290
KPE: KPK_1793
PFL: PFL_3836
PRW: PsycPRwf_2348
NOC: Noc_1924
MMW: Mmwyl1_0144
RSO: RSc2664(dld)
RPI: Rpic_2900
RPF: Rpic12D_2494
REU: Reut_A2787
REH: H16_A3091(dld)
RME: Rmet_2924
BMA: BMA2415 BMAA0959
BMV: BMASAVP1_0419 BMASAVP1_A0332
BML: BMA10229_0224 BMA10229_A1193
BMN: BMA10247_2602 BMA10247_A1377
BPS: BPSL2842 BPSS1318
BPM: BURPS1710b_1859 BURPS1710b_3341 BURPS1710b_A0337
BPL: BURPS1106A_3329 BURPS1106A_A1787
BPD: BURPS668_3295 BURPS668_A1873
BTE: BTH_I1292
BVI: Bcep1808_0696
BUR: Bcep18194_A3301 Bcep18194_A3820 Bcep18194_A3821 Bcep18194_A4598
Bcep18194_C7432
BCM: Bcenmc03_0703
BAM: Bamb_0625 Bamb_6129
BXE: Bxe_A3977
BPE: BP2906
BPA: BPP2490
BBR: BB1937
RFR: Rfer_1477
POL: Bpro_0111 Bpro_2755
PNA: Pnap_0069
AAV: Aave_0095
AJS: Ajs_0040
VEI: Veis_0025 Veis_4691
DIA: Dtpsy_0061
MPT: Mpe_A3774
HAR: HEAR1203 HEAR2733
EBA: ebA3803(dldH)
AZO: azo1166 azo3432(dld)
DAR: Daro_0268
APP: CAP2UW1_3508
HPA: HPAG1_1164
HAC: Hac_1598(dld)
DVL: Dvul_2154 Dvul_2544 Dvul_2725
DDE: Dde_0182
ADE: Adeh_2867
ACP: A2cp1_3047
MLO: mll1488
MES: Meso_1985
RET: RHE_CH02804(dld)
RLE: RL0959 RL3261
BME: BMEI0599
BMF: BAB1_1429
BMB: BruAb1_1405
BMS: BR1410
BOV: BOV_1366
BJA: bll2678 bll6558
BRA: BRADO2057 BRADO5280 BRADO5609
BBT: BBta_2386 BBta_5731 BBta_6133
RPA: RPA3503
RPB: RPB_2026
RPE: RPE_2140 RPE_4381
XAU: Xaut_1422
MRD: Mrad2831_5949
MET: M446_2035
MNO: Mnod_0518
SIL: SPO0634
SIT: TM1040_0483
RSP: RSP_0177 RSP_2120
RSH: Rsph17029_0795 Rsph17029_1811
RSQ: Rsph17025_0705
JAN: Jann_1163 Jann_1937
RDE: RD1_3435
PDE: Pden_2187
DSH: Dshi_1361(dld1)
NAR: Saro_0816
GOX: GOX2071
ACR: Acry_1462
RRU: Rru_A0442 Rru_A0777 Rru_A1124 Rru_A1299
MAG: amb2985
BAN: BA3575
BAR: GBAA3575
BAA: BA_4067
BAT: BAS3315
BCE: BC3504
BCA: BCE_3530
BCZ: BCZK3230(glcD)
BTK: BT9727_3278
BTL: BALH_3165
OIH: OB1259 OB1357
GKA: GK3215
GTN: GTNG_3136
AMT: Amet_0764
MMC: Mmcs_3961
MKM: Mkms_4035
MJL: Mjls_3975
RHA: RHA1_ro03236 RHA1_ro08314
NCA: Noca_2155
FRA: Francci3_0962 Francci3_1983 Francci3_2007
SEN: SACE_3640 SACE_3788
CAI: Caci_5973
RXY: Rxyl_2833
FJO: Fjoh_2129 Fjoh_4811
AVA: Ava_4556
TER: Tery_4091
CCH: Cag_0799 Cag_1163
CPH: Cpha266_0816
PVI: Cvib_1206
PLT: Plut_0570
RRS: RoseRS_1612 RoseRS_3360
RCA: Rcas_3429 Rcas_4146
CAU: Caur_2132 Caur_2134
CAG: Cagg_1529
CHL: Chy400_2298 Chy400_2300
DRA: DR_1026
DGE: Dgeo_2410
MBU: Mbur_1773
NPH: NP3764A(dld_1)
MSE: Msed_0436 Msed_1118
PAI: PAE2035
PIS: Pisl_1344 Pisl_1837
PCL: Pcal_1218
PAS: Pars_0490 Pars_2089
 |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:13950255]
GREGOLIN C, SINGER TP.
The lactic dehydrogenase of yeast. III. D(-)Lactic cytochrome c
reductase, a zinc-flavoprotein from aerobic yeast.
Biochim. Biophys. Acta. 67 (1963) 201-18.
Saccharomyces cerevisiae [GN:sce] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13901630]
GREGOLIN C, SINGER TP, KEARNEY EB, BOERI E.
The formation and enzymatic properties of the various lactic
dehydrogenases of yeast.
Ann. N. Y. Acad. Sci. 94 (1961) 780-97.
Saccharomyces cerevisiae [GN:sce] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:13729965]
NYGAARD AP.
D(-)-Lactic cytochrome c reductase, a flavo-protein from yeast.
J. Biol. Chem. 236 (1961) 920-5.
Saccharomyces cerevisiae [GN:sce] |
|---|
Reference
Authors
Title
Journal
|
4
Nygaard, A.P.
Lactate dehydrogenases of yeast.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 7, Academic Press, New York, 1963, p. 557-565. |
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| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.2.4
IUBMB Enzyme Nomenclature: 1.1.2.4
ExPASy - ENZYME nomenclature database: 1.1.2.4
BRENDA, the Enzyme Database: 1.1.2.4
CAS: 37250-79-6 |
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