KEGG   ENZYME: 1.1.3.6Help
Entry
EC 1.1.3.6                  Enzyme                                 
Name cholesterol oxidase;
cholesterol- O2 oxidoreductase;
3beta-hydroxy steroid oxidoreductase;
3beta-hydroxysteroid:oxygen oxidoreductase
Class Oxidoreductases;
Acting on the CH-OH group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname cholesterol:oxygen oxidoreductase
Reaction(IUBMB) cholesterol + O2 = cholest-4-en-3-one + H2O2 [RN:R01459]
Reaction(KEGG) R01459
Show
Substrate cholesterol [CPD:C00187];
O2 [CPD:C00007]
Product cholest-4-en-3-one [CPD:C00599];
H2O2 [CPD:C00027]
Pathway PATH: ec00100  Steroid biosynthesis
Orthology KO: K03333  cholesterol oxidase
Genes PFO: Pfl01_5219
CJA: CJA_0537(choB)
PRW: PsycPRwf_0069
ACB: A1S_1119
ABY: ABAYE2620
ABN: AB57_1203
ABB: ABBFA_002425
HCH: HCH_01642
ABO: ABO_1259
CVI: CV_2218
RSO: RS05823(RSp1167)
REH: H16_A1655(betA3)
BMA: BMAA2022
BMV: BMASAVP1_1045
BML: BMA10229_1332
BMN: BMA10247_A2312
BPS: BPSS2278
BPM: BURPS1710b_A1417
BPL: BURPS1106A_A3075
BPD: BURPS668_A3202
BTE: BTH_II2309
BXE: Bxe_B1816
BPH: Bphy_5113
BPY: Bphyt_4847
RFR: Rfer_0318
LCH: Lcho_3191
BBA: Bd0736(choA) Bd2646(choD)
DAL: Dalk_4295
ADE: Adeh_3081
ACP: A2cp1_3274
AFW: Anae109_3076
ANK: AnaeK_3180
MXA: MXAN_5165
SCL: sce0787
HOH: Hoch_5037
MTU: Rv3409c(choD)
MTC: MT3517
MRA: MRA_3449(choD)
MTF: TBFG_13443
MTB: TBMG_03460(TBMG_03460.1)
MBO: Mb3443c(choD)
MBB: BCG_3479c(choD)
MBT: JTY_3479(choD)
MLE: ML0389(choD)
MLB: MLBr_00389(choD)
MAV: MAV_4354
MSM: MSMEG_1604
MUL: MUL_0903(choD)
MVA: Mvan_1514
MGI: Mflv_4906
MAB: MAB_3719c
MMC: Mmcs_1170
MKM: Mkms_1187
MJL: Mjls_1197
MMI: MMAR_1140(choD)
CJK: jk0629(choE)
CUR: cur_1318
NFA: nfa26130
RHA: RHA1_ro03863 RHA1_ro04305(choD) RHA1_ro06201(choD)
RER: RER_04330 RER_10120(choE) RER_19350 RER_28410
ROP: ROP_42140 ROP_62610
GBR: Gbro_1204 Gbro_1728 Gbro_2398 Gbro_2399 Gbro_4774
SCO: SCO4781(SCD63.13)
SMA: SAV_5017(choD)
SGR: SGR_2748 SGR_477
ART: Arth_1255
XCE: Xcel_2031
NCA: Noca_3632
TFU: Tfu_2332
TCU: Tcur_1996 Tcur_4248
SRO: Sros_1176 Sros_4246
FRA: Francci3_4446
FRE: Franean1_0121 Franean1_3356 Franean1_3901
FAL: FRAAL6768(choA)
NML: Namu_2922
SEN: SACE_6417(pteG) SACE_6705(choD)
SVI: Svir_04760 Svir_13500 Svir_30650
AMI: Amir_2425 Amir_3746 Amir_6532
STP: Strop_2611 Strop_3834
SAQ: Sare_2810 Sare_4224
CAI: Caci_2199 Caci_5961
LIL: LA3998 LA3999(choB) LA4009(choA)
LIC: LIC13194(choB) LIC13195
LBL: LBL_0185
LBI: LEPBI_I0286(choB)
LBF: LBF_0277
ABA: Acid345_0361
SUS: Acid_5726
SYD: Syncc9605_0826
NPU: Npun_F2280 Npun_R6526
Taxonomy
Structures PDB: 1B4V  1B8S  1CBO  1CC2  1COY  1I19  1IJH  1MXT  1N1P  1N4U  
     1N4V  1N4W  2GEW  2I0K  3B3R  3B6D  3CNJ  3COX  3GYI  3GYJ  
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:4757363]
Richmond W.
Preparation and properties of a cholesterol oxidase from Nocardia
sp. and its application to the enzymatic assay of total cholesterol
in serum.
Clin. Chem. 19 (1973) 1350-6.
Nocardia sp.
Reference
  Authors
  Title
  Journal
  Organism
 2  [PMID:13143010]
STADTMAN TC, CHERKES A, ANFINSEN CB.
Studies on the microbiological degradation of cholesterol.
J. Biol. Chem. 206 (1954) 511-23.
Mycobacterium sp.
Other DBs ExplorEnz - The Enzyme Database: 1.1.3.6
IUBMB Enzyme Nomenclature: 1.1.3.6
ExPASy - ENZYME nomenclature database: 1.1.3.6
BRENDA, the Enzyme Database: 1.1.3.6
CAS: 9028-76-6
DBGET integrated database retrieval system