| Entry |
|
|---|
| Name |
gluconate 2-dehydrogenase (acceptor);
gluconate oxidase;
gluconate dehydrogenase;
gluconic dehydrogenase;
D-gluconate dehydrogenase;
gluconic acid dehydrogenase;
2-ketogluconate reductase;
D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding;
D-gluconate:(acceptor) 2-oxidoreductase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With other acceptors
 |
|---|
| Sysname |
D-gluconate:acceptor 2-oxidoreductase |
|---|
| Reaction(IUBMB) |
D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor
[RN:R01742] |
|---|
| Reaction(KEGG) |
R01742 > R01741
 |
|---|
| Substrate |
D-gluconate [CPD:C00257];
acceptor [CPD:C00028] |
|---|
| Product |
2-dehydro-D-gluconate [CPD:C06473];
reduced acceptor [CPD:C00030] |
|---|
| Cofactor |
FAD [CPD:C00016] |
|---|
| Comment |
A flavoprotein (FAD). |
|---|
| Pathway |
PATH: ec00030 Pentose phosphate pathway
PATH: ec01100 Metabolic pathways |
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| Orthology |
KO: K06151 gluconate 2-dehydrogenase alpha chain
KO: K06152 gluconate 2-dehydrogenase gamma chain |
|---|
| Genes |
ETA: ETA_30600 ETA_30610
KPN: KPN_02083 KPN_02084
KPE: KPK_2249 KPK_2250
KPU: KP1_3158 KP1_3160
SPE: Spro_2015 Spro_2016 Spro_2136 Spro_2137
PAE: PA2264 PA2265
PAU: PA14_35290(gnd) PA14_35300
PAP: PSPA7_2975 PSPA7_2976
PAG: PLES_30391 PLES_30401
PPU: PP_3383 PP_3384
PPF: Pput_2375 Pput_2376
PPG: PputGB1_2561 PputGB1_2562
PPW: PputW619_2564 PputW619_2565
PFL: PFL_0053 PFL_0054
PFO: Pfl01_0085 Pfl01_0086
PFS: PFLU0051 PFLU0052
AVN: Avin_00890(gadh3) Avin_00900(gadh1)
RME: Rmet_2503 Rmet_2504
BVI: Bcep1808_4793 Bcep1808_4794
BUR: Bcep18194_B1793 Bcep18194_B1794
BCN: Bcen_4142 Bcen_4143
BCH: Bcen2424_4223 Bcen2424_4224
BCM: Bcenmc03_3293 Bcenmc03_3294
BCJ: BCAM1356 BCAM1357
BAM: Bamb_3645 Bamb_3646
BAC: BamMC406_4119 BamMC406_4120
BMU: Bmul_4381 Bmul_4382
BMJ: BMULJ_04124 BMULJ_04125
BXE: Bxe_A4094 Bxe_A4095 Bxe_C0230
BPY: Bphyt_4639 Bphyt_4640 Bphyt_6209 Bphyt_6210
BPA: BPP2079 BPP2080
BBR: BB1475 BB1476
BPT: Bpet3834 Bpet3835
BAV: BAV3248 BAV3249
VEI: Veis_1597 Veis_1598
VAP: Vapar_5398 Vapar_5399
CTT: CtCNB1_2719 CtCNB1_2720
CJE: Cj0414 Cj0415
CJR: CJE0463 CJE0464
CJJ: CJJ81176_0438 CJJ81176_0439
CJU: C8J_0389 C8J_0390
RHI: NGR_b01110 NGR_b01120 NGR_b01130
OAN: Oant_3608 Oant_3609
NHA: Nham_4243 Nham_4244
AZC: AZC_2718 AZC_2719
MPO: Mpop_4202 Mpop_4203
DSH: Dshi_3895 Dshi_3896
GOX: GOX1231 GOX1232
GDI: GDI_0854 GDI_0855
GDJ: Gdia_1164 Gdia_1165
GYM: GYMC10_2887 GYMC10_2888
LSP: Bsph_0678 Bsph_0679
BBE: BBR47_55430 BBR47_55440
PJD: Pjdr2_2941 Pjdr2_2942
ART: Arth_1924
SUS: Acid_5750 Acid_5751
OTE: Oter_2178
GAU: GAU_1078
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6815420]
Matsushita K, Shinagawa E, Ameyama M.
D-Gluconate dehydrogenase from bacteria,
2-keto-D-gluconate-yielding, membrane-bound.
Methods. Enzymol. 89 Pt D (1982) 187-93.
Klebsiella pneumoniae, Pseudomonas aeruginosa, Pseudomonas
fluorescens, Serratia marcescens |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13239635]
RAMAKRISHNAN T, CAMPBELL JJ.
Gluconic dehydrogenase of Pseudomonas aeruginosa.
Biochim. Biophys. Acta. 17 (1955) 122-7.
Pseudomonas aeruginosa |
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| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.99.3
IUBMB Enzyme Nomenclature: 1.1.99.3
ExPASy - ENZYME nomenclature database: 1.1.99.3
BRENDA, the Enzyme Database: 1.1.99.3
CAS: 9028-81-3 |
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