KEGG   ENZYME: 1.10.3.2Help
Entry
EC 1.10.3.2                 Enzyme                                 

Name
laccase;
urishiol oxidase;
urushiol oxidase;
p-diphenol oxidase
Class
Oxidoreductases;
Acting on diphenols and related substances as donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
benzenediol:oxygen oxidoreductase
Reaction(IUBMB)
4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O [RN:R00083]
Reaction(KEGG)
Substrate
benzenediol [CPD:C01785];
O2 [CPD:C00007]
Product
benzosemiquinone [CPD:C05309];
H2O [CPD:C00001]
Comment
A group of multi-copper proteins of low specificity acting on both o- and p-quinols, and often acting also on aminophenols and phenylenediamine. The semiquinone may react further either enzymically or non-enzymically.
History
EC 1.10.3.2 created 1961, deleted 1972, reinstated 1978
Orthology
K05909  
Genes
DHA: 
PIC: 
MGR: 
AFM: 
CNE: 
UMA: 
TTH: 
Taxonomy
Reference
1
  Authors
Dawson, C.R. and Tarpley, W.B.
  Title
The copper oxidases.
  Journal
In: Sumner, J.B. and Myrback, K. (Eds.), The Enzymes, 1st ed., vol. 2, Academic Press, New York, 1951, p. 454-498.
Reference
2
  Authors
Keilin, D. and Mann, T.
  Title
Laccase, a blue copper-protein oxidase from the latex of Rhus succedanea.
  Journal
Nature (Lond.) 143 (1939) 23-24.
Reference
3
  Authors
Malmstrom, B.G., Andreasson, L.-E. and Reinhammar, B.
  Title
Copper-containing oxidases and superoxide dismutase.
  Journal
In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 12, Academic Press, New York, 1975, p. 507-579.
Reference
4
  Authors
Mayer, A.M. and Harel, E.
  Title
Polyphenol oxidases in plants.
  Journal
Phytochemistry 18 (1979) 193-215.
Reference
5  [PMID:13584395]
  Authors
NAKAMURA T.
  Title
Purification and physico-chemical properties of laccase.
  Journal
Biochim. Biophys. Acta. 30 (1958) 44-52.
  Organism
Rhus vernicifera
Reference
6  [PMID:13618260]
  Authors
NAKAMURA T.
  Title
Stoichiometric studies on the action of laccase.
  Journal
Biochim. Biophys. Acta. 30 (1958) 538-42.
  Organism
Rhus vernicifera
Reference
7  [PMID:14304827]
  Authors
PEISACH J, LEVINE WG.
  Title
A COMPARISON OF THE ENZYMIC ACTIVITIES OF PIG CERULOPLASMIN AND RHUS VERNICIFERA LACCASE.
  Journal
J. Biol. Chem. 240 (1965) 2284-9.
  Organism
Sus scofa, Rhus vernicifera
Reference
8
  Authors
Reinhammar, B. and Malmstrom, B.G.
  Title
"Blue" copper-containing oxidases.
  Journal
In: Spiro, T.G. (Ed.), Copper Proteins, Copper Proteins, New York, 1981, p. 109-149.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
80498-15-3

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