KEGG   ENZYME: 1.10.3.3Help
Entry
EC 1.10.3.3                 Enzyme                                 

Name
L-ascorbate oxidase;
ascorbase;
ascorbic acid oxidase;
ascorbate oxidase;
ascorbic oxidase;
ascorbate dehydrogenase;
L-ascorbic acid oxidase;
AAO;
L-ascorbate:O2 oxidoreductase;
AA oxidase
Class
Oxidoreductases;
Acting on diphenols and related substances as donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
L-ascorbate:oxygen oxidoreductase
Reaction(IUBMB)
4 L-ascorbate + O2 = 4 monodehydroascorbate + 2 H2O [RN:R00068]
Reaction(KEGG)
Substrate
L-ascorbate [CPD:C00072];
O2 [CPD:C00007]
Product
monodehydroascorbate [CPD:C01041];
H2O [CPD:C00001]
Comment
A multicopper protein.
History
EC 1.10.3.3 created 1961, modified 2011
Pathway
Ascorbate and aldarate metabolism
Metabolic pathways
Orthology
K00423  
L-ascorbate oxidase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
POPTR_0001s03760g(POPTRDRAFT_750403) POPTR_0001s03770g(POPTRDRAFT_547564) POPTR_0001s22680g(POPTRDRAFT_1067783) POPTR_0003s20670g POPTR_0003s20680g(POPTRDRAFT_555163) POPTR_0009s16130g(POPTRDRAFT_1086023)
VVI: 
SLY: 
SOT: 
DOSA: 
Os06t0567200-01(Os06g0567200)
OBR: 
BDI: 
SBI: 
SORBI_10g022430(SORBIDRAFT_10g022430)
ZMA: 
SITA: 
SMO: 
PPP: 
CCP: 
XFA: 
XFT: 
XFM: 
XFN: 
XFF: 
MAQ: 
RSO: 
RS04807(RSp1530)
BPM: 
BUR: 
BXE: 
RET: 
BRA: 
BBT: 
NAR: 
 » show all
Taxonomy
Reference
1  [PMID:13787201]
  Authors
YAMAZAKI I, PIETTE LH
  Title
Mechanism of free radical formation and disappearance during the ascorbic acid oxidase and peroxidase reactions.
  Journal
Biochim. Biophys. Acta. 50 (1961) 62-9.
Reference
2
  Authors
Stark, G.R. and Dawson, C.R.
  Title
Ascorbic acid oxidase.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 8, Academic Press, New York, 1963, p. 297-311.
Reference
3  [PMID:1548698]
  Authors
Messerschmidt A, Ladenstein R, Huber R, Bolognesi M, Avigliano L, Petruzzelli R, Rossi A, Finazzi-Agro A
  Title
Refined crystal structure of ascorbate oxidase at 1.9 A resolution.
  Journal
J. Mol. Biol. 224 (1992) 179-205.
  Organism
Cucurbita pepo
  Sequence
[up:P37064]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9029-44-1

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