KEGG   ENZYME: 1.12.98.2Help
Entry
EC 1.12.98.2                Enzyme                                 

Name
5,10-methenyltetrahydromethanopterin hydrogenase;
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase;
nonmetal hydrogenase;
N5,N10-methenyltetrahydromethanopterin hydrogenase;
hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase
Class
Oxidoreductases;
Acting on hydrogen as donor;
With other, known, acceptors
BRITE hierarchy
Sysname
hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase
Reaction(IUBMB)
H2 + 5,10-methenyltetrahydromethanopterin = H+ + 5,10-methylenetetrahydromethanopterin [RN:R04455]
Reaction(KEGG)
Substrate
H2 [CPD:C00282];
5,10-methenyltetrahydromethanopterin [CPD:C04330]
Product
H+ [CPD:C00080];
5,10-methylenetetrahydromethanopterin [CPD:C04377]
Comment
Does not catalyse the reduction of artificial dyes. Does not by itself catalyse a H2/H+ exchange reaction. Does not contain nickel or iron-sulfur clusters.
History
EC 1.12.98.2 created 1999 as EC 1.12.99.4, transferred 2002 to EC 1.12.98.2, modified 2004
Pathway
Methane metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K13942  
5,10-methenyltetrahydromethanopterin hydrogenase
Genes
MJA: 
MFE: 
MVU: 
MFS: 
MIF: 
MIG: 
MMP: 
MMP0127(hmd)
MMQ: 
MMX: 
MMZ: 
MMD: 
MAE: 
MVN: 
MVO: 
MOK: 
MLA: 
MPI: 
MFO: 
MTH: 
MMG: 
MSI: 
MRU: 
MEB: 
MFV: 
MKA: 
MK0013(Hmd)
 » show all
Taxonomy
Reference
1
  Authors
Zirngibl, C., Hedderich, R. and Thauer, R.K.
  Title
N5,N10-Methylenetetrahydromethanopterin dehydrogenase from Methanobacterium thermoautotrophicum has hydrogenase activity.
  Journal
FEBS Lett. 261 (1990) 112-116.
Reference
2  [PMID:7628605]
  Authors
Klein AR, Fernandez VM, Thauer RK.
  Title
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase: mechanism of H2 formation analyzed using hydrogen isotopes.
  Journal
FEBS. Lett. 368 (1995) 203-6.
  Organism
Methanobacterium thermoautotrophicum
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
100357-01-5

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