| Entry |
|
| Name |
catechol 2,3-dioxygenase;
2,3-pyrocatechase;
catechol 2,3-oxygenase;
catechol oxygenase;
metapyrocatechase;
pyrocatechol 2,3-dioxygenase
|
| Class |
Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2;
With incorporation of two atoms of oxygen
 |
| Sysname |
catechol:oxygen 2,3-oxidoreductase (decyclizing)
|
| Reaction(IUBMB) |
catechol + O2 = 2-hydroxymuconate semialdehyde [RN: R00816]
|
| Reaction(KEGG) |
|
| Substrate |
|
| Product |
2-hydroxymuconate semialdehyde [CPD: C00682]
|
| Comment |
Requires FeII. The enzyme from Alcaligenes sp. strain O-1 has also been shown to catalyse the reaction: 2,3-dihydroxybenzenesulfonate + O2 + H2O = 2-hydroxymuconate + bisulfite and has been referred to as 2,3-dihydroxybenzenesulfonate 2,3-dioxygenase. Further work will be necessary to show whether or not this is a distinct enzyme.
|
| Pathway |
| Chlorocyclohexane and chlorobenzene degradation | | Benzoate degradation | | Xylene degradation | | Styrene degradation | | Metabolic pathways | | Microbial metabolism in diverse environments |
|
| Orthology |
|
| Genes |
PAO: | | PSD: | | PSC: | | AVN: | | MAD: | | RPI: | | RPF: | | REU: | | REH: | | RME: | | CNC: | | BVI: | | BUR: | | BCT: | | BAV: | | AJS: | | VEI: | | CTT: | | ADN: | | ADK: | | MPT: | | LCH: | | AZO: | | DAR: | | TMZ: | | ARC: | | MCI: | | MES: | | RHI: | | ARA: | | REC: | | RLE: | | RLT: | | BMF: | | BMB: | | BMC: | | BMT: | | BMR: | | BJA: | | BJU: | | BRA: | | BBT: | | BRS: | | RPA: | | RPB: | | RPD: | | RPT: | | MSL: | | PHL: | | SIT: | | RSP: | | RSH: | | JAN: | | NAR: | | NPP: | | SJP: | | PGV: | | GTH: | | GCT: | | GMC: | | AAC: | | BTS: | | SIV: | | TMR: | | SAY: | | SAP: | | CAR: | | NFA: | | RHA: | | ROP: | | GBR: | | SMA: | | SVL: | | MTS: | | ART: | | ACH: | | ICA: | | TCU: | | BSD: | | MMAR: | | AMD: | | PDX: | | RXY: | | CWO: | | TPI: | | SLI: | | RSI: | | RRS: | | RCA: | | CAU: | | CAG: | | CHL: | | TRO: | | STI: | | CAP: | | DRA: | | DGE: | | TTH: | | TTJ: | | TTL: | | TSC: | | THC: | | MRB: | | MHD: | | SSO: | | STO: | | SAI: | | SIS: | | SID: | | SIN: | | SII: | | MSE: | | » show all
 |
| Reference |
|
| Authors |
Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM. |
| Title |
Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid. |
| Journal |
Biochem. J. 300 ( Pt 2) (1994) 429-36. |
| Organism |
Alcaligenes sp. |
| Reference |
|
| Authors |
Junker F, Leisinger T, Cook AM. |
| Title |
3-Sulphocatechol 2,3-dioxygenase and other dioxygenases (EC 1.13.11.2 and EC 1.14.12.-) in the degradative pathways of 2-aminobenzenesulphonic, benzenesulphonic and 4-toluenesulphonic acids in Alcaligenes sp. strain O-1. |
| Journal |
Microbiology. 140 ( Pt 7) (1994) 1713-22. |
| Organism |
Alcaligenes sp. |
| Reference |
3 |
| Authors |
Hayaishi, O. |
| Title |
Direct oxygenation by O2, oxygenases. |
| Journal |
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 8, Academic Press, New York, 1963, p. 353-371. |
| Reference |
|
| Authors |
KOJIMA Y, ITADA N, HAYAISHI O. |
| Title |
Metapyrocatachase: a new catechol-cleaving enzyme. |
| Journal |
J. Biol. Chem. 236 (1961) 2223-8. |
| Organism |
Pseudomonas sp. |
| Reference |
|
| Authors |
NOZAKI M, KAGAMIYAMA H, HAYAISHI O. |
| Title |
METAPYROCATECHASE. I. PURIFICATION, CRYSTALLIZATION AND SOME PROPERTIES. |
| Journal |
Biochem. Z. 338 (1963) 582-90. |
| Organism |
Pseudomonas arvilla |
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: UM-BBD (Biocatalysis/Biodegradation Database): BRENDA, the Enzyme Database: CAS: 9029-46-3 |