KEGG   ENZYME: 1.13.11.20Help
Entry
EC 1.13.11.20               Enzyme                                 
Name cysteine dioxygenase;
cysteine oxidase
Class Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of
oxygen into the substrate (oxygenases). The oxygen incorporated need
not be derived from O2;
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname L-cysteine:oxygen oxidoreductase
Reaction(IUBMB) L-cysteine + O2 = 3-sulfinoalanine [RN:R00893]
Reaction(KEGG) R00893
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Substrate L-cysteine [CPD:C00097];
O2 [CPD:C00007]
Product 3-sulfinoalanine [CPD:C00606]
Cofactor NADH [CPD:C00004];
NADPH [CPD:C00005];
Iron [CPD:C00023]
Comment Requires Fe2+ and NAD(P)H.
Pathway PATH: ec00270  Cysteine and methionine metabolism
PATH: ec00430  Taurine and hypotaurine metabolism
PATH: ec01100  Metabolic pathways
Orthology KO: K00456  cysteine dioxygenase
Genes HSA: 1036(CDO1)
PTR: 462010(CDO1)
MCC: 696387(CDO1)
MMU: 12583(Cdo1)
RNO: 81718(Cdo1)
CFA: 474637(CDO1)
BTA: 514462(CDO1)
MDO: 100015236
GGA: 427391(CDO1)
XLA: 398963 443755
XTR: 394737
DRE: 393714(cdo1)
BFO: BRAFLDRAFT_82885
SPU: 575999
DME: Dmel_CG5493
DPO: Dpse_GA18925
DAN: Dana_GF12941
DER: Dere_GG20963
DPE: Dper_GL17444
DSE: Dsec_GM19895
DSI: Dsim_GD25380
DYA: Dyak_GE13903
DGR: Dgri_GH21607
DMO: Dmoj_GI19578
AGA: AgaP_AGAP005153
AAG: AaeL_AAEL007416
CQU: CpipJ_CPIJ020056
AME: 726371
TCA: 663314
CEL: F56F10.3
CBR: CBG20456
SMM: Smp_165750
NVE: NEMVE_v1g107308
HMG: 100204586
TAD: TRIADDRAFT_49766
PIC: PICST_43654(CDG1)
PPA: PAS_chr2-2_0322
LEL: LELG_05361
CTP: CTRG_05906
YLI: YALI0F11627g
NCR: NCU06625
PAN: PODANSg7426
MGR: MGG_06095
FGR: FG09820.1
ANI: AN4081.2
AFM: AFUA_1G05570 AFUA_5G14410
AOR: AO090011000009 AO090020000659
ANG: An04g07230 An18g04410
AFV: AFLA_097690
PCS: Pc18g02180 Pc21g04760
NFI: NFIA_019200 NFIA_072490
CIM: CIMG_03912
URE: UREG_02026
SSL: SS1G_00064
BFU: BC1G_11718
DDI: DDB_0231093
ABA: Acid345_2687
Taxonomy
Structures PDB: 2ATF  2B5H  2GH2  2IC1  2Q4S  3ELN  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:5767301]
Lombardini JB, Singer TP, Boyer PD.
Cystein oxygenase. II. Studies on the mechanism of the reaction with
18oxygen.
J. Biol. Chem. 244 (1969) 1172-5.
Rattus norvegicus [GN:rno]
Other DBs ExplorEnz - The Enzyme Database: 1.13.11.20
IUBMB Enzyme Nomenclature: 1.13.11.20
ExPASy - ENZYME nomenclature database: 1.13.11.20
BRENDA, the Enzyme Database: 1.13.11.20
CAS: 37256-59-0
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