KEGG   ENZYME: 1.13.11.37Help
Entry
EC 1.13.11.37               Enzyme                                 

Name
hydroxyquinol 1,2-dioxygenase;
hydroxyquinol dioxygenase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)
Reaction(IUBMB)
benzene-1,2,4-triol + O2 = maleylacetate [RN:R04061]
Reaction(KEGG)
R04061;
(other) R03891
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Substrate
benzene-1,2,4-triol [CPD:C02814];
O2 [CPD:C00007]
Product
maleylacetate [CPD:C02222]
Comment
An iron protein. Highly specific; catechol and pyrogallol are acted on at less than 1% of the rate at which hydroxyquinol is oxidized.
History
EC 1.13.11.37 created 1989, modified 2013
Pathway
Chlorocyclohexane and chlorobenzene degradation
Benzoate degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K04098  
hydroxyquinol 1,2-dioxygenase
Genes
PPUN: 
PFE: 
REU: 
REH: 
H16_B0968(pcpA)
CNC: 
BPR: 
BUR: 
BCM: 
BCJ: 
BAM: 
BPY: 
BUG: 
BGF: 
BGD: 
BYI: 
BPX: 
POL: 
AAA: 
VEI: 
VAP: 
VPE: 
VPD: 
HSE: 
LCH: 
SMI: 
BJA: 
BJU: 
BRS: 
AOL: 
AZC: 
MNO: 
PHL: 
SWI: 
SJP: 
SCH: 
MSA: 
MVA: 
CGL: 
NCgl2951(Cgl3056)
CGB: 
cg3385(catA3)
CGU: 
CGT: 
CGS: 
CGG: 
CGM: 
CHN: 
CMD: 
CGY: 
RHA: 
ROP: 
ROA: 
SCB: 
SBH: 
SRC: 
ACH: 
BSD: 
BLASA_2968(chqB2)
AMN: 
AMM: 
AMES_4795(catA)
AMZ: 
B737_4795(catA)
PDX: 
ACTN: 
CAI: 
ONI: 
 » show all
Taxonomy
Reference
1  [PMID:6539772]
  Authors
Sze IS, Dagley S.
  Title
Properties of salicylate hydroxylase and hydroxyquinol 1,2-dioxygenase purified from Trichosporon cutaneum.
  Journal
J. Bacteriol. 159 (1984) 353-9.
  Organism
Trichosporon cutaneum
Reference
2  [PMID:15772073]
  Authors
Ferraroni M, Seifert J, Travkin VM, Thiel M, Kaschabek S, Scozzafava A, Golovleva L, Schlomann M, Briganti F
  Title
Crystal structure of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex  3E, a key enzyme involved in polychlorinated aromatics biodegradation.
  Journal
J. Biol. Chem. 280 (2005) 21144-54.
  Organism
Nocardioides simplex
  Sequence
[up:Q5PXQ6]
Reference
3  [PMID:16232466]
  Authors
Hatta T, Nakano O, Imai N, Takizawa N, Kiyohara H
  Title
Cloning and sequence analysis of hydroxyquinol 1,2-dioxygenase gene in 2,4,6-trichlorophenol-degrading Ralstonia pickettii DTP0602 and characterization  of its product.
  Journal
J. Biosci. Bioeng. 87 (1999) 267-72.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
91847-14-2

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