| Entry |
|
|---|
| Name |
1-hydroxy-2-naphthoate 1,2-dioxygenase;
1-hydroxy-2-naphthoate dioxygenase;
1-hydroxy-2-naphthoate-degrading enzyme;
1-hydroxy-2-naphthoic acid dioxygenase |
|---|
| Class |
Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of
oxygen into the substrate (oxygenases). The oxygen incorporated need
not be derived from O2;
With incorporation of two atoms of oxygen
 |
|---|
| Sysname |
1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing) |
|---|
| Reaction(IUBMB) |
1-hydroxy-2-naphthoate + O2 =
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate [RN:R07657] |
|---|
| Reaction(KEGG) |
R07657;
(other) R03466
 |
|---|
| Substrate |
1-hydroxy-2-naphthoate [CPD:C03203];
O2 [CPD:C00007] |
|---|
| Product |
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate [CPD:C16149] |
|---|
| Cofactor |
Iron [CPD:C00023] |
|---|
| Comment |
Requires Fe2+. Involved, with EC 4.1.2.34
4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase, in the metabolism of
phenanthrene in bacteria. |
|---|
| Pathway |
PATH: ec00626 Naphthalene and anthracene degradation |
|---|
| Orthology |
KO: K11948 1-hydroxy-2-naphthoate dioxygenase |
|---|
| Genes |
MVA: Mvan_0468
MGI: Mflv_0589
MMC: Mmcs_1628
MKM: Mkms_1654
MJL: Mjls_1601
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6833175]
Barnsley EA.
Phthalate pathway of phenanthrene metabolism: formation of
2'-carboxybenzalpyruvate.
J. Bacteriol. 154 (1983) 113-7.
gram-negative coccus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.13.11.38
IUBMB Enzyme Nomenclature: 1.13.11.38
ExPASy - ENZYME nomenclature database: 1.13.11.38
UM-BBD (Biocatalysis/Biodegradation Database): 1.13.11.38
BRENDA, the Enzyme Database: 1.13.11.38
CAS: 85941-64-6 |
|---|
