KEGG   ENZYME: 1.13.11.57Help
Entry
EC 1.13.11.57               Enzyme                                 

Name
gallate dioxygenase;
GalA
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
BRITE hierarchy
Sysname
gallate:oxygen oxidoreductase
Reaction(IUBMB)
gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate [RN:R09565]
Reaction(KEGG)
R09565;
(other) R03550
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Substrate
gallate [CPD:C01424];
O2 [CPD:C00007]
Product
(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate [CPD:C04434]
Comment
Contains non-heme Fe2+. The enzyme is a ring-cleavage dioxygenase that acts specifically on gallate to produce the keto-tautomer of 4-oxalomesaconate [1,2].
History
EC 1.13.11.57 created 2011
Pathway
Aminobenzoate degradation
Microbial metabolism in diverse environments
Orthology
K04099  
gallate dioxygenase
Genes
EAM: 
EAMY_1944(pcaH)
EAY: 
EBI: 
KPN: 
KPU: 
KPM: 
KPP: 
KPE: 
KPR: 
KPJ: 
KPI: 
KVA: 
CRO: 
SPE: 
SMAF: 
SERR: 
RAH: 
RAA: 
ROR: 
PPU: 
PPF: 
PPW: 
PPB: 
PPI: 
PPX: 
PPUT: 
PPUN: 
AVN: 
AVL: 
AVD: 
CSA: 
PSE: 
RSL: 
RME: 
BUR: 
BMU: 
BMJ: 
BPH: 
BGD: 
BYI: 
BUO: 
CDN: 
ACK: 
VEI: 
Veis_0170(pcmA)
VPE: 
VPD: 
BRA: 
BRADO1853(ligB)
BBT: 
BBta_2174(ligB)
AEX: 
SSY: 
SLG_03330(desB)
PGV: 
KSK: 
KSE_75140(pcmA)
ART: 
Arth_4373(pcmA)
APN: 
 » show all
Taxonomy
Reference
1  [PMID:16030014]
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Garcia JL, Diaz E
  Title
Molecular characterization of the gallate dioxygenase from Pseudomonas putida KT2440. The prototype of a new subgroup of extradiol dioxygenases.
  Journal
J. Biol. Chem. 280 (2005) 35382-90.
  Organism
Pseudomonas putida
  Sequence
[up:Q88JX5] [ppu:PP_2518]
Reference
2  [PMID:21219457]
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
  Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
  Journal
Mol. Microbiol. 79 (2011) 359-74.
  Organism
Pseudomonas putida
  Sequence
[up:Q88JX5] [ppu:PP_2518]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 

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