| Entry |
|
|---|
| Name |
arginine 2-monooxygenase;
arginine monooxygenase;
arginine decarboxylase;
arginine oxygenase (decarboxylating);
arginine decarboxy-oxidase |
|---|
| Class |
Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of
oxygen into the substrate (oxygenases). The oxygen incorporated need
not be derived from O2;
With incorporation of one atom of oxygen (internal monooxygenases or
internal mixed-function oxidases)
 |
|---|
| Sysname |
L-arginine:oxygen 2-oxidoreductase (decarboxylating) |
|---|
| Reaction(IUBMB) |
L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O [RN:R00559] |
|---|
| Reaction(KEGG) |
R00559
 |
|---|
| Substrate |
L-arginine [CPD:C00062];
O2 [CPD:C00007] |
|---|
| Product |
4-guanidinobutanamide [CPD:C03078];
CO2 [CPD:C00011];
H2O [CPD:C00001] |
|---|
| Cofactor |
FAD [CPD:C00016];
Flavoprotein [CPD:C06411] |
|---|
| Comment |
A flavoprotein. Also acts on canavanine and homoarginine. |
|---|
| Pathway |
PATH: ec00330 Arginine and proline metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4295160]
Olomucki A, Pho DB, Lebar R, Delcambe L, Thoai NV.
[Arginine oxygenase (decarboxylating). V. Purification and flavin
nature]
Biochim. Biophys. Acta. 151 (1968) 353-66.
Streptomyces griseus [GN:sgr] |
|---|
Reference
Authors
Title
Journal
|
2
Thoai, N.V. and Olomucki, A.
Arginine decarboxy-oxydase. I. Caracteres et nature de l'enzyme.
Biochim. Biophys. Acta 59 (1962) 533-544. |
|---|
Reference
Authors
Title
Journal
|
3
Thoai, N.V. and Olomucki, A.
Arginine decarboxy-oxydase. II. Oxydation de la canavanine et de
l'homoarginine en beta-guanidopropionamide et en
delta-guanidovaleramide.
Biochim. Biophys. Acta 59 (1962) 545-552. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.13.12.1
IUBMB Enzyme Nomenclature: 1.13.12.1
ExPASy - ENZYME nomenclature database: 1.13.12.1
BRENDA, the Enzyme Database: 1.13.12.1
CAS: 9027-36-5 |
|---|
