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Entry
EC 1.13.12.13               Enzyme                                 

Name
Oplophorus-luciferin 2-monooxygenase;
Oplophorus luciferase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
BRITE hierarchy
Sysname
Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating)
Reaction(IUBMB)
Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu [RN:R07128]
Reaction(KEGG)
Substrate
Oplophorus luciferin [CPD:C15037];
O2 [CPD:C00007]
Product
oxidized Oplophorus luciferin [CPD:C15038];
CO2 [CPD:C00011];
hnu [CPD:C00205]
Comment
The luciferase from the deep sea shrimp Oplophorus gracilorostris is a complex composed of more than one protein. The enzyme's specificity is quite broad, with both coelenterazine and bisdeoxycoelenterazine being good substrates.
History
EC 1.13.12.13 created 2004
Reference
1  [PMID:629957]
  Authors
Shimomura O, Masugi T, Johnson FH, Haneda Y.
  Title
Properties and reaction mechanism of the bioluminescence system of the deep-sea shrimp Oplophorus gracilorostris.
  Journal
Biochemistry. 17 (1978) 994-8.
  Sequence
[up:Q9GV45]
Reference
2  [PMID:10984608]
  Authors
Inouye S, Watanabe K, Nakamura H, Shimomura O.
  Title
Secretional luciferase of the luminous shrimp Oplophorus gracilirostris: cDNA cloning of a novel imidazopyrazinone luciferase(1).
  Journal
FEBS. Lett. 481 (2000) 19-25.
  Sequence
[up:Q9GV45]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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