KEGG   ENZYME: 1.13.12.3Help
Entry
EC 1.13.12.3                Enzyme                                 
Name tryptophan 2-monooxygenase
Class Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of
oxygen into the substrate (oxygenases). The oxygen incorporated need
not be derived from O2;
With incorporation of one atom of oxygen (internal monooxygenases or
internal mixed-function oxidases)
BRITE hierarchy
Sysname L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)
Reaction(IUBMB) L-tryptophan + O2 = (indol-3-yl)acetamide + CO2 + H2O [RN:R00679]
Reaction(KEGG) R00679
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Substrate L-tryptophan [CPD:C00078];
O2 [CPD:C00007]
Product (indol-3-yl)acetamide [CPD:C02693];
CO2 [CPD:C00011];
H2O [CPD:C00001]
Pathway PATH: ec00380  Tryptophan metabolism
PATH: ec01070  Biosynthesis of plant hormones
Orthology KO: K00466  tryptophan 2-monooxygenase
Genes DZE: Dd1591_3740
PAP: PSPA7_3191
PPU: PP_0383
PPF: Pput_0407
PPG: PputGB1_0411
PPW: PputW619_4820
PST: PSPTO_0518
PSB: Psyr_1536 Psyr_4667
PSP: PSPPH_4701
PFL: PFL_5670
PFO: Pfl01_5154
PFS: PFLU5595
PEN: PSEEN0401
RSO: RSc3151
BVI: Bcep1808_4425
BCM: Bcenmc03_4304
BXE: Bxe_C1245
BPH: Bphy_7769
ATU: Atu6011(tms1)
ATC: AGR_pTi_49(iaaM)
AVI: Avi_8288(tms1)
RDE: RD1_1495
ACR: Acry_2670
MAB: MAB_0818
RHA: RHA1_ro03531
RER: RER_05790
ROP: ROP_33250
SCO: SCO1454(SCL6.11c)
SMA: SAV_6893
SGR: SGR_6070
ART: Arth_1110
AAU: AAur_1221
ACH: Achl_1186
KRA: Krad_1432
CAI: Caci_8157
Taxonomy
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:5916389]
Kosuge T, Heskett MG, Wilson EE.
Microbial synthesis and degradation of indole-3-acetic acid. I. The
conversion of L-tryptophan to indole-3-acetamide by an enzyme system
from Pseudomonas savastanoi.
J. Biol. Chem. 241 (1966) 3738-44.
Pseudomonas savastanoi
Reference
  Authors
  Title

  Journal
 2
Kuo, T.T. and Kosuge, T.
Factors influencing the production and further metabolism of
indole-3-acetic acid by Pseudomonas savastanoi.
J. Gen. Appl. Microbiol. 15 (1969) 51-63.
Other DBs ExplorEnz - The Enzyme Database: 1.13.12.3
IUBMB Enzyme Nomenclature: 1.13.12.3
ExPASy - ENZYME nomenclature database: 1.13.12.3
BRENDA, the Enzyme Database: 1.13.12.3
CAS: 37256-65-8
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