| Entry |
|
|---|
| Name |
phenylalanine 2-monooxygenase;
L-phenylalanine oxidase (deaminating and decarboxylating);
phenylalanine (deaminating, decarboxylating)oxidase |
|---|
| Class |
Oxidoreductases;
Acting on single donors with O2 as oxidant and incorporation of
oxygen into the substrate (oxygenases). The oxygen incorporated need
not be derived from O2;
With incorporation of one atom of oxygen (internal monooxygenases or
internal mixed-function oxidases)
 |
|---|
| Sysname |
L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating) |
|---|
| Reaction(IUBMB) |
L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O [RN:R00690] |
|---|
| Reaction(KEGG) |
R00690
 |
|---|
| Substrate |
L-phenylalanine [CPD:C00079];
O2 [CPD:C00007] |
|---|
| Product |
2-phenylacetamide [CPD:C02505];
CO2 [CPD:C00011];
H2O [CPD:C00001] |
|---|
| Comment |
The reaction shown above is about 80% of the reaction catalysed; the
remaining 20% is: L-phenylalanine + O2 + H2O = 3-phenylpyruvic acid
+ ammonia + H2O2 a reaction similar to that of EC 1.4.3.2,
L-amino-acid oxidase. |
|---|
| Pathway |
PATH: ec00360 Phenylalanine metabolism |
|---|
| Structures |
PDB: 2YR4 2YR5 2YR6 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:7174643]
Koyama H.
Purification and characterization of a novel L-phenylalanine oxidase
(Deaminating and decarboxylating) from Pseudomonas sp. P-501.
J. Biochem. (Tokyo). 92 (1982) 1235-40.
Pseudomonas sp. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:6501250]
Koyama H.
Oxidation and oxygenation of L-amino acids catalyzed by a
L-phenylalanine oxidase (deaminating and decarboxylating) from
Pseudomonas sp. P-501.
J. Biochem. (Tokyo). 96 (1984) 421-7.
Pseudomonas sp. |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:6692570]
Koyama H.
A simple and rapid enzymatic determination of L-phenylalanine with a
novel L-phenylalanine oxidase (deaminating and decarboxylating) from
Pseudomonas sp. P-501.
Clin. Chim. Acta. 136 (1984) 131-6.
Pseudomonas sp. |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:3818566]
Koyama H, Suzuki H.
Spectral and kinetic studies on Pseudomonas L-phenylalanine oxidase
(deaminating and decarboxylating).
J. Biochem. (Tokyo). 100 (1986) 859-66.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.13.12.9
IUBMB Enzyme Nomenclature: 1.13.12.9
ExPASy - ENZYME nomenclature database: 1.13.12.9
BRENDA, the Enzyme Database: 1.13.12.9
CAS: 190396-37-3 |
|---|
