leucocyanidin oxygenase;
anthocyanidin synthase

Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2;
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

leucocyanidin,2-oxoglutarate:oxygen oxidoreductase

leucocyanidin + 2-oxoglutarate + O2 = cis- and trans-dihydroquercetins + succinate + CO2 + 2 H2O [RN:R05723 R07366]

R05723 R07366;
(other) R04276 R05036 R05037 R06540

leucocyanidin [CPD:C05906];
2-oxoglutarate [CPD:C00026];
O2 [CPD:C00007]

The enzyme requires Fe(II) and ascorbate. It is involved in the pathway by which many flowering plants make anthocyanin (glycosylated anthocyandin) flower pigments. The intermediates are transformed into cis- and trans-dihydroquercetin [2], which the enzyme can also oxidize to quercetin. Acidification of the products gives anthocyanidin [1], which, however, may not be a natural precursor of the anthocyanins.

1  [PMID:10074715]

Saito K, Kobayashi M, Gong Z, Tanaka Y, Yamazaki M.

Direct evidence for anthocyanidin synthase as a 2-oxoglutarate-dependent oxygenase: molecular cloning and functional expression of cDNA from a red forma of Perilla frutescens.

Plant. J. 17 (1999) 181-9.

Perilla frutescens

2

Turnbull, J.J., Sobey, W.J., Aplin, R.T., Hassan, A., Firmin, J.L., Schofield, C.J. and Prescott, A.G.

Are anthocyanidins the immediate products of anthocyanidin synthase?.

Chem. Commun. (2000) 2473-2474.