| Entry |
|
|---|
| Name |
terephthalate 1,2-dioxygenase;
benzene-1,4-dicarboxylate 1,2-dioxygenase;
1,4-dicarboxybenzoate 1,2-dioxygenase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of two atoms of
oxygen into the other donor
 |
|---|
| Sysname |
benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase
(1,2-hydroxylating) |
|---|
| Reaction(IUBMB) |
terephthalate + NADH + H+ + O2 =
(1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate + NAD+
[RN:R05148] |
|---|
| Reaction(KEGG) |
R05148
 |
|---|
| Substrate |
terephthalate [CPD:C06337];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007] |
|---|
| Product |
(1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate [CPD:C06318];
NAD+ [CPD:C00003] |
|---|
| Comment |
Has been shown to contain a Rieske [2Fe-2S] cluster |
|---|
| Pathway |
PATH: ec00623 2,4-Dichlorobenzoate degradation |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:7961417]
Schlafli HR, Weiss MA, Leisinger T, Cook AM.
Terephthalate 1,2-dioxygenase system from Comamonas testosteroni
T-2: purification and some properties of the oxygenase component.
J. Bacteriol. 176 (1994) 6644-52.
Comamonas testosteroni |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.12.15
IUBMB Enzyme Nomenclature: 1.14.12.15
ExPASy - ENZYME nomenclature database: 1.14.12.15
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.12.15
BRENDA, the Enzyme Database: 1.14.12.15
CAS: 162032-76-0 |
|---|
