| Entry |
|
|---|
| Name |
trans-cinnamate 2-monooxygenase;
cinnamic acid 2-hydroxylase;
cinnamate 2-monooxygenase;
cinnamic 2-hydroxylase;
cinnamate 2-hydroxylase;
trans-cinnamic acid 2-hydroxylase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen into the other donor
 |
|---|
| Sysname |
trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating) |
|---|
| Reaction(IUBMB) |
trans-cinnamate + NADPH + H+ + O2 = 2-hydroxycinnamate + NADP+ + H2O
[RN:R02254] |
|---|
| Reaction(KEGG) |
R02254
 |
|---|
| Substrate |
trans-cinnamate [CPD:C00423];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007] |
|---|
| Product |
2-hydroxycinnamate [CPD:C01772];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Pathway |
PATH: ec00360 Phenylalanine metabolism
PATH: ec00940 Phenylpropanoid biosynthesis |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4153528]
Gestetner B, Conn EE.
The 2-hydroxylation of trans-cinnamic acid by chloroplasts from
Melilotus alba Desr.
Arch. Biochem. Biophys. 163 (1974) 617-24.
Melilotus alba |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.13.14
IUBMB Enzyme Nomenclature: 1.14.13.14
ExPASy - ENZYME nomenclature database: 1.14.13.14
BRENDA, the Enzyme Database: 1.14.13.14
CAS: 53126-56-0 |
|---|
