KEGG   ENZYME: 1.14.13.21Help
Entry
EC 1.14.13.21               Enzyme                                 

Name
flavonoid 3'-monooxygenase;
flavonoid 3'-hydroxylase;
flavonoid 3-hydroxylase (erroneous);
NADPH:flavonoid-3'-hydroxylase;
flavonoid 3-monooxygenase (erroneous)
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating)
Reaction(IUBMB)
a flavonoid + NADPH + H+ + O2 = a 3'-hydroxyflavonoid + NADP+ + H2O [RN:R03615]
Reaction(KEGG)
Substrate
flavonoid [CPD:C01579];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
3'-hydroxyflavonoid [CPD:C02790];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Acts on a number of flavonoids, including naringenin and dihydrokaempferol. Does not act on 4-coumarate or 4-coumaroyl-CoA.
History
EC 1.14.13.21 created 1983
Pathway
Flavonoid biosynthesis
Flavone and flavonol biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K05280  
flavonoid 3'-monooxygenase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
PPER: 
PMUM: 
MDM: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0013s07050g(POPTRDRAFT_823742)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os10t0317900-01(Os10g0317900) Os10t0320100-01(Os10g0320100)
OBR: 
BDI: 
SBI: 
SORBI_04g024710(SORBIDRAFT_04g024710) SORBI_04g024730(SORBIDRAFT_04g024730) SORBI_04g024750(SORBIDRAFT_04g024750) SORBI_07g005753(SORBIDRAFT_07g005753) SORBI_09g022480(SORBIDRAFT_09g022480) SORBI_10g020495(SORBIDRAFT_10g020495)
ZMA: 
SITA: 
PDA: 
ATR: 
s00110p00149730(AMTR_s00110p00149730)
PPP: 
 » show all
Taxonomy
Reference
1
  Authors
Forkmann, G., Heller, W. and Grisebach, H.
  Title
Anthocyanin biosynthesis in flowers of Matthiola incana flavanone 3- and flavonoid 3'-hydroxylases.
  Journal
Z. Naturforsch. C: Biosci. 35 (1980) 691-695.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
75991-44-5

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