KEGG   ENZYME: 1.14.13.21Help
Entry
EC 1.14.13.21               Enzyme                                 
Name
flavonoid 3'-monooxygenase;
flavonoid 3'-hydroxylase;
flavonoid 3-hydroxylase (erroneous);
NADPH:flavonoid-3'-hydroxylase;
flavonoid 3-monooxygenase (erroneous)
Class
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating)
Reaction(IUBMB)
a flavonoid + NADPH + H+ + O2 = a 3'-hydroxyflavonoid + NADP+ + H2O [RN:R03615]
Reaction(KEGG)
Substrate
flavonoid [CPD:C01579];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
3'-hydroxyflavonoid [CPD:C02790];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Acts on a number of flavonoids, including naringenin and dihydrokaempferol. Does not act on 4-coumarate or 4-coumaroyl-CoA.
Pathway
Flavonoid biosynthesis
Flavone and flavonol biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K05280  
flavonoid 3'-monooxygenase
Genes
ATH: 
ALY: 
GMX: 
547475(SF3'H1)
MTR: 
RCU: 
POP: 
VVI: 
OSA: 
DOSA: 
Os10t0320100-01(Os10g0320100)
BDI: 
SBI: 
SORBI_04g024710(SORBIDRAFT_04g024710) SORBI_04g024730(SORBIDRAFT_04g024730) SORBI_04g024750(SORBIDRAFT_04g024750)
ZMA: 
100273383 100279887
 » show all
Taxonomy
Reference
1
  Authors
Forkmann, G., Heller, W. and Grisebach, H.
  Title
Anthocyanin biosynthesis in flowers of Matthiola incana flavanone 3- and flavonoid 3'-hydroxylases.
  Journal
Z. Naturforsch. C: Biosci. 35 (1980) 691-695.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
75991-44-5
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