| Entry |
|
| Name |
phosphatidylcholine 12-monooxygenase;
ricinoleic acid synthase;
oleate Delta12-hydroxylase;
oleate Delta12-monooxygenase |
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen into the other donor
 |
| Sysname |
1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen
oxidoreductase (12-hydroxylating) |
| Reaction(IUBMB) |
1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NADH + H+ + O2 =
1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + NAD+ +
H2O [RN:R03476] |
| Reaction(KEGG) |
R03476
 |
| Substrate |
1-acyl-2-oleoyl-sn-glycero-3-phosphocholine [CPD:C01282];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007] |
| Product |
1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine
[CPD:C04792];
NAD+ [CPD:C00003];
H2O [CPD:C00001] |
Reference Authors Title
Journal Organism
|
1 [PMID:4289003]
Galliard T, Stumpf PK.
Fat metabolism in higher plants. 30. Enzymatic synthesis of
ricinoleic acid by a microsomal preparation from developing Ricinus
communis seeds.
J. Biol. Chem. 241 (1966) 5806-12.
Ricinus communis [GN:rcu] |
Reference Authors Title
Journal Organism
|
2 [PMID:16661734]
Moreau RA, Stumpf PK.
Recent Studies of the Enzymic Synthesis of Ricinoleic Acid by
Developing Castor Beans.
Plant. Physiol. 67 (1981) 672-676.
Ricinus communis [GN:rcu] |
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.13.26
IUBMB Enzyme Nomenclature: 1.14.13.26
ExPASy - ENZYME nomenclature database: 1.14.13.26
BRENDA, the Enzyme Database: 1.14.13.26
CAS: 77950-95-9 |