KEGG   ENZYME: 1.14.13.26Help
Entry
EC 1.14.13.26               Enzyme                                 

Name phosphatidylcholine 12-monooxygenase;
ricinoleic acid synthase;
oleate Delta12-hydroxylase;
oleate Delta12-monooxygenase
Class Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen into the other donor
BRITE hierarchy
Sysname 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen
oxidoreductase (12-hydroxylating)
Reaction(IUBMB) 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NADH + H+ + O2 =
1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + NAD+ +
H2O [RN:R03476]
Reaction(KEGG) R03476
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Substrate 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine [CPD:C01282];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine
[CPD:C04792];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Reference
  Authors
  Title


  Journal
  Organism
1  [PMID:4289003]
Galliard T, Stumpf PK.
Fat metabolism in higher plants. 30. Enzymatic synthesis of
ricinoleic acid by a microsomal preparation from developing Ricinus
communis seeds.
J. Biol. Chem. 241 (1966) 5806-12.
Ricinus communis [GN:rcu]
Reference
  Authors
  Title

  Journal
  Organism
2  [PMID:16661734]
Moreau RA, Stumpf PK.
Recent Studies of the Enzymic Synthesis of Ricinoleic Acid by
Developing Castor Beans.
Plant. Physiol. 67 (1981) 672-676.
Ricinus communis [GN:rcu]
Other DBs ExplorEnz - The Enzyme Database: 1.14.13.26
IUBMB Enzyme Nomenclature: 1.14.13.26
ExPASy - ENZYME nomenclature database: 1.14.13.26
BRENDA, the Enzyme Database: 1.14.13.26
CAS: 77950-95-9

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