| Entry |
|
|---|
| Name |
4-nitrophenol 2-monooxygenase;
4-nitrophenol hydroxylase;
4-nitrophenol-2-hydroxylase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen into the other donor
 |
|---|
| Sysname |
4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating) |
|---|
| Reaction(IUBMB) |
4-nitrophenol + NADH + H+ + O2 = 4-nitrocatechol + NAD+ + H2O
[RN:R03023] |
|---|
| Reaction(KEGG) |
R03023
 |
|---|
| Substrate |
4-nitrophenol [CPD:C00870];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007] |
|---|
| Product |
4-nitrocatechol [CPD:C02235];
NAD+ [CPD:C00003];
H2O [CPD:C00001] |
|---|
| Cofactor |
FAD [CPD:C00016] |
|---|
| Comment |
A flavoprotein (FAD). |
|---|
| Pathway |
PATH: ec00361 gamma-Hexachlorocyclohexane degradation |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6477623]
Mitra D, Vaidyanathan CS.
A new 4-nitrophenol 2-hydroxylase from a Nocardia sp.
Biochem. Int. 8 (1984) 609-15.
Nocardia sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.13.29
IUBMB Enzyme Nomenclature: 1.14.13.29
ExPASy - ENZYME nomenclature database: 1.14.13.29
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.13.29
BRENDA, the Enzyme Database: 1.14.13.29
CAS: 91116-87-9 |
|---|
