| Entry |
|
|---|
| Name |
6-oxocineole dehydrogenase;
6-oxocineole oxygenase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
With NADH or NADPH as one donor, and incorporation of one atom of
oxygen into the other donor
 |
|---|
| Sysname |
6-oxocineole,NADPH:oxygen oxidoreductase |
|---|
| Reaction(IUBMB) |
6-oxocineole + NADPH + H+ + O2 =
1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + NADP+ + H2O
[RN:R02995] |
|---|
| Reaction(KEGG) |
R02995
 |
|---|
| Substrate |
6-oxocineole [CPD:C00848];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007] |
|---|
| Product |
1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one [CPD:C04718];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Comment |
The product undergoes non-enzymic cleavage and subsequent ring
closure to form the lactone
4,5-dihydro-5,5-dimethyl-4-(3-oxobutyl)furan-2(3H)-one. |
|---|
| Pathway |
PATH: ec00902 Monoterpenoid biosynthesis |
|---|
Reference
Authors
Title
Journal
|
1
Williams, D.R., Trudgill, P.W. and Taylor, D.G.
Metabolism of 1,8-cineole by Rhodococcus species: ring cleavage
reactions.
J. Gen. Microbiol. 135 (1989) 1957-1967. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.13.51
IUBMB Enzyme Nomenclature: 1.14.13.51
ExPASy - ENZYME nomenclature database: 1.14.13.51
BRENDA, the Enzyme Database: 1.14.13.51
CAS: 122933-80-6 |
|---|
