KEGG   ENZYME: 1.14.13.58Help
Entry
EC 1.14.13.58               Enzyme                                 

Name
benzoyl-CoA 3-monooxygenase;
benzoyl-CoA 3-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
benzoyl-CoA + NADPH + H+ + O2 = 3-hydroxybenzoyl-CoA + NADP+ + H2O [RN:R02449]
Reaction(KEGG)
Substrate
benzoyl-CoA [CPD:C00512];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
3-hydroxybenzoyl-CoA [CPD:C05195];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
The enzyme from the denitrifying bacterium Pseudomonas KB740 catalyses a flavin-requiring reaction (FAD or FMN). Benzoate is not a substrate.
History
EC 1.14.13.58 created 1999
Reference
1  [PMID:7851381]
  Authors
Niemetz R, Altenschmidt U, Brucker S, Fuchs G.
  Title
Benzoyl-coenzyme-A 3-monooxygenase, a flavin-dependent hydroxylase. Purification, some properties and its role in aerobic benzoate oxidation via gentisate in a denitrifying bacterium.
  Journal
Eur. J. Biochem. 227 (1995) 161-8.
  Organism
Pseudomonas sp.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
151616-61-4

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