| Entry |
|
|---|
| Name |
progesterone 11alpha-monooxygenase;
progesterone 11alpha-hydroxylase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
Miscellaneous
 |
|---|
| Sysname |
progesterone,hydrogen-donor:oxygen oxidoreductase
(11alpha-hydroxylating) |
|---|
| Reaction(IUBMB) |
progesterone + AH2 + O2 = 11alpha-hydroxyprogesterone + A + H2O
[RN:R02214] |
|---|
| Reaction(KEGG) |
R02214
 |
|---|
| Substrate |
progesterone [CPD:C00410];
AH2 [CPD:C00030];
O2 [CPD:C00007] |
|---|
| Product |
11alpha-hydroxyprogesterone [CPD:C03747];
A [CPD:C00028];
H2O [CPD:C00001] |
|---|
| Pathway |
PATH: ec00140 Steroid hormone biosynthesis |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5417182]
Shibahara M, Moody JA, Smith LL.
Microbial hydroxylations. V. 11-alpha-hydroxylation of progesterone
by cell-free preparations of Aspergillus ochraceus.
Biochim. Biophys. Acta. 202 (1970) 172-9.
Aspergillus ochraceus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.99.14
IUBMB Enzyme Nomenclature: 1.14.99.14
ExPASy - ENZYME nomenclature database: 1.14.99.14
BRENDA, the Enzyme Database: 1.14.99.14
CAS: 37256-77-2 |
|---|
