myristoyl-CoA 11-(Z) desaturase;
n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(Z) desaturating]

Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2;
Miscellaneous

n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(Z) desaturating]

myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O [RN:R05322 R07217]

R05322 R07217

myristoyl-CoA [CPD:C02593];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]

Involved in sex pheromone synthesis in the moth Spodoptera littoralis. (Z)-11-Tetradecenoyl-CoA is formed by stereospecific removal of H from the pro-R positions at C-11 and C-12. EC 1.14.99.31, myristoyl-CoA 11-(E) desaturase, forms the (E)-isomer by removing the pro-R H group at C-11 and the pro-S H group at C-12.

1

Navaro, I., Font, I., Fabrias, G. and Camps, F.

Stereospecificity of the (E)- and (Z)-11 myristoyl desaturases in the biosynthesis of Spodoptera littoralis sex pheromone.

J. Am. Chem. Soc. 119 (1997) 11335-11336.