KEGG   ENZYME: 1.2.1.13Help
Entry
EC 1.2.1.13                 Enzyme                                 

Name
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating);
triosephosphate dehydrogenase (NADP+);
dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating);
glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating);
NADP+-glyceraldehyde-3-phosphate dehydrogenase;
NADP+-glyceraldehyde phosphate dehydrogenase;
NADP+-dependent glyceraldehyde phosphate dehydrogenase;
NADP+-triose phosphate dehydrogenase;
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating);
GAPDH
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)
Reaction(IUBMB)
D-glyceraldehyde 3-phosphate + phosphate + NADP+ = 3-phospho-D-glyceroyl phosphate + NADPH + H+ [RN:R01063]
Reaction(KEGG)
Substrate
D-glyceraldehyde 3-phosphate [CPD:C00118];
phosphate [CPD:C00009];
NADP+ [CPD:C00006]
Product
3-phospho-D-glyceroyl phosphate [CPD:C00236];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.2.1.13 created 1961
Pathway
Carbon fixation in photosynthetic organisms
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K05298  
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
Genes
ATH: 
AT1G12900(GAPA-2) AT1G42970(GAPB) AT3G26650(GAPA)
ALY: 
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POP: 
POPTR_0002s00840g(POPTRDRAFT_412234) POPTR_0002s22600g POPTR_0005s27550g(POPTRDRAFT_831715) POPTR_0014s13660g(POPTRDRAFT_824231)
VVI: 
SLY: 
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OSA: 
DOSA: 
Os03t0129300-01(Os03g0129300)
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PDA: 
MUS: 
ATR: 
s00016p00251680(AMTR_s00016p00251680) s00044p00131190(AMTR_s00044p00131190)
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 » show all
Taxonomy
Reference
1  [PMID:13804190]
  Authors
BRENNEMAN FN, VOLK WA.
  Title
Glyceraldehyde phosphate dehydrogenase activity with triphosphopyridine nucleotide and with diphosphopyridine nucleotide.
  Journal
J. Biol. Chem. 234 (1959) 2443-7.
Reference
2
  Authors
Gibbs, M.
  Title
TPN triosephosphate dehydrogenase from plant tissue.
  Journal
Methods Enzymol. 1 (1955) 411-415.
Reference
3  [PMID:13271400]
  Authors
ROSENBERG LL, ARNON DI.
  Title
The preparation and properties of a new glyceraldehyde-3-phosphate dehydrogenase from photosynthetic tissues.
  Journal
J. Biol. Chem. 217 (1955) 361-71.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-87-6

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