KEGG   ENZYME: 1.2.1.22Help
Entry
EC 1.2.1.22                 Enzyme                                 
Name lactaldehyde dehydrogenase;
L-lactaldehyde:NAD oxidoreductase;
nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase
Class Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname (S)-lactaldehyde:NAD+ oxidoreductase
Reaction(IUBMB) (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + 2 H+
[RN:R01446]
Reaction(KEGG) R01446;
(other) R00203
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Substrate (S)-lactaldehyde [CPD:C00424];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product (S)-lactate [CPD:C00186];
NADH [CPD:C00004];
H+ [CPD:C00080]
Pathway PATH: ec00620  Pyruvate metabolism
Orthology KO: K00138  lactaldehyde dehydrogenase
Genes LMA: LmjF36.5180
ECO: b1415(aldA) b3588(aldB)
ECJ: JW1412(aldA) JW3561(aldB)
ECD: ECDH10B_1541(aldA)
EBW: BWG_1242(aldA)
ECE: Z2306(aldA) Z5008(aldB)
ECS: ECs2021 ECs4464
ECF: ECH74115_2021(aldA) ECH74115_4958(aldB)
ETW: ECSP_1897(aldA) ECSP_4580(aldB)
ECG: E2348C_1553(aldA) E2348C_3837(aldB)
ECC: c1842(aldA) c4408(aldB)
ECI: UTI89_C1637(aldA) UTI89_C4129(aldB)
ECP: ECP_1420
ECV: APECO1_2866(aldB) APECO1_566(aldA)
ECW: EcE24377A_1596(aldA) EcE24377A_4086(aldB)
ECX: EcHS_A1498(aldA)
ECM: EcSMS35_1757(aldA) EcSMS35_3915(aldB)
ECY: ECSE_1498 ECSE_3865
ECL: EcolC_0125 EcolC_2243
ECK: EC55989_1546(aldA) EC55989_4046(aldB)
ECQ: ECED1_1573(aldA) ECED1_4273(aldB)
ECR: ECIAI1_1410(aldA) ECIAI1_3756(aldB)
ECZ: ECS88_1511(aldA) ECS88_4004(aldB)
EUM: ECUMN_1663(aldA)
ELF: LF82_0064(aldA)
EBL: B21_01382(aldA)
EBD: ECBD_2225
EBR: ECB_01370(aldA)
EOH: ECO103_1547(aldA)
EOJ: ECO26_2014(aldA)
STY: STY4116(aldB)
STT: t3839(aldB)
SPT: SPA3531(aldB)
SEK: SSPA3297
SPQ: SPAB_04573
SEI: SPC_3760(aldB)
SEC: SC3604(aldB)
SEH: SeHA_C4003(aldB)
SEE: SNSL254_A3958(aldB)
SEW: SeSA_A3879(aldB)
SEA: SeAg_B3894(aldB)
SED: SeD_A4065(aldB)
SEG: SG3750(aldB)
SET: SEN3502(aldB)
SES: SARI_03969
STM: STM3680(aldB)
SFL: SF1797(aldA) SF3626(aldB)
SFX: S1475(aldA) S4142(aldB)
SFV: SFV_1791(aldA) SFV_3945(aldB)
SBO: SBO_1672(aldA) SBO_3588(aldB)
SBC: SbBS512_E1635(aldA) SbBS512_E4003(aldB)
ECA: ECA0094(aldB) ECA0118(aldA)
PCT: PC1_4133
PWA: Pecwa_4414
ENT: Ent638_0143 Ent638_1953
ESA: ESA_01703
CTU: Ctu_22550(aldA)
KPN: KPN_01501(aldA)
KPE: KPK_2959(aldA)
KPU: KP1_2509(aldA)
CKO: CKO_01448 CKO_05043
PPW: PputW619_2695
AVN: Avin_09240(aldB)
PAT: Patl_2553
SDE: Sde_2645
NMA: NMA0480(aldA)
NME: NMB1968(aldA)
NMC: NMC1942(aldA)
NMN: NMCC_0245(aldA)
NMI: NMO_0201(aldA)
NGK: NGK_2585
REH: H16_A1919
BUR: Bcep18194_B2835
BXE: Bxe_B1123 Bxe_C1106
BPY: Bphyt_1990
VEI: Veis_4949
DAC: Daci_0293
MPT: Mpe_A0361
MFA: Mfla_1995
CJE: Cj0490(ald')
CJR: CJE0539(aldA)
CJD: JJD26997_1445(aldA)
CFF: CFF8240_0070
DAT: HRM2_03640(aldA)
SMD: Smed_2446
RHI: NGR_b14320
BME: BMEII0140
CCR: CC_3580
GOX: GOX1712
GDI: GDI_1287(aldA)
GDJ: Gdia_1997
OIH: OB0492
AFL: Aflv_1182(gabD)
SEP: SE2067
SER: SERP2080
SHA: SH0552
SSP: SSP1629
LCA: LSEI_2424
LCB: LCABL_25950(aldA)
OOE: OEOE_0324
MSY: MS53_0078(aldA)
SCO: SCO3486(SCE65.22)
SHI: Shel_05560
SUS: Acid_0037
BVU: BVU_1789
PDI: BDI_2087
FNU: FN0454
ANA: all5022
TAC: Ta0809
TVO: TVN1021
Taxonomy
Structures PDB: 2HG2  2ILU  2IMP  2OPX  
Reference
  Authors
  Title

  Journal
 1  [PMID:5821022]
Rembold H, Simmersbach F.
Catabolism of pteridine cofactors. II. A specific pterin deaminase
in rat liver.
Biochim. Biophys. Acta. 184 (1969) 589-96.
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:4310089]
Sridhara S, Wu TT.
Purification and properties of lactaldehyde dehydrogenase from
Escherichia coli.
J. Biol. Chem. 244 (1969) 5233-8.
Escherichia coli [GN:eco]
Other DBs ExplorEnz - The Enzyme Database: 1.2.1.22
IUBMB Enzyme Nomenclature: 1.2.1.22
ExPASy - ENZYME nomenclature database: 1.2.1.22
BRENDA, the Enzyme Database: 1.2.1.22
CAS: 37250-90-1
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