| Entry |
|
|---|
| Name |
aryl-aldehyde dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
aryl-aldehyde:NAD+ oxidoreductase |
|---|
| Reaction(IUBMB) |
an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+
[RN:R01486] |
|---|
| Reaction(KEGG) |
R01486 > R02655 R02695 R03300 R05235
 |
|---|
| Substrate |
aromatic aldehyde [CPD:C00193];
NAD+ [CPD:C00003];
H2O [CPD:C00001] |
|---|
| Product |
aromatic acid [CPD:C00539];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Comment |
Oxidizes a number of aromatic aldehydes, but not aliphatic
aldehydes. |
|---|
| Pathway |
PATH: ec00350 Tyrosine metabolism
PATH: ec00621 Biphenyl degradation
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4289834]
Raison JK, Henson G, Rienits KG.
The oxidation of gentisaldehyde by nicotinamide-adenine
dinucleotide-specific, aromatic aldehyde dehydrogenase from rabbit
liver.
Biochim. Biophys. Acta. 118 (1966) 285-98.
Oryctolagus cuniculus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.1.29
IUBMB Enzyme Nomenclature: 1.2.1.29
ExPASy - ENZYME nomenclature database: 1.2.1.29
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.29
BRENDA, the Enzyme Database: 1.2.1.29
CAS: 37250-94-5 |
|---|
