| Entry |
|
|---|
| Name |
4-hydroxyphenylacetaldehyde dehydrogenase;
4-HPAL dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase |
|---|
| Reaction(IUBMB) |
4-hydroxyphenylacetaldehyde + NAD+ + H2O = 4-hydroxyphenylacetate +
NADH + 2 H+ [RN:R02695] |
|---|
| Reaction(KEGG) |
R02695
 |
|---|
| Substrate |
4-hydroxyphenylacetaldehyde [CPD:C03765];
NAD+ [CPD:C00003];
H2O [CPD:C00001] |
|---|
| Product |
4-hydroxyphenylacetate [CPD:C00642];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Comment |
With EC 4.2.1.87 octopamine dehydratase, brings about the metabolism
of octopamine in Pseudomonas. |
|---|
| Pathway |
PATH: ec00350 Tyrosine metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3034855]
Cuskey SM, Peccoraro V, Olsen RH.
Initial catabolism of aromatic biogenic amines by Pseudomonas
aeruginosa PAO: pathway description, mapping of mutations, and
cloning of essential genes.
J. Bacteriol. 169 (1987) 2398-404.
Pseudomonas aeruginosa [GN:pae] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.1.53
IUBMB Enzyme Nomenclature: 1.2.1.53
ExPASy - ENZYME nomenclature database: 1.2.1.53
BRENDA, the Enzyme Database: 1.2.1.53
CAS: 109456-56-6 |
|---|
