| Entry |
|
|---|
| Name |
gamma-guanidinobutyraldehyde dehydrogenase;
alpha-guanidinobutyraldehyde dehydrogenase;
4-guanidinobutyraldehyde dehydrogenase;
GBAL dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
4-guanidinobutanal:NAD+ 1-oxidoreductase |
|---|
| Reaction(IUBMB) |
4-guanidinobutanal + NAD+ + H2O = 4-guanidinobutanoate + NADH + 2 H+
[RN:R03177] |
|---|
| Reaction(KEGG) |
R03177
 |
|---|
| Substrate |
4-guanidinobutanal [CPD:C02647];
NAD+ [CPD:C00003];
H2O [CPD:C00001] |
|---|
| Product |
4-guanidinobutanoate [CPD:C01035];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Comment |
Involved in the degradation of arginine in Pseudomonas putida (cf.
EC 1.2.1.19 aminobutyraldehyde dehydrogenase). |
|---|
| Pathway |
PATH: ec00330 Arginine and proline metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K12254 4-guanidinobutyraldehyde dehydrogenase / NAD-dependent
aldehyde dehydrogenase |
|---|
| Genes |
PAE: PA5312
PAU: PA14_70140(aldH)
PAP: PSPA7_6087
PAG: PLES_57071
PPU: PP_5278
PPF: Pput_5188
PPG: PputGB1_5330
PPW: PputW619_0192
PST: PSPTO_0092
PSB: Psyr_0227
PSP: PSPPH_0215
PFL: PFL_6046
PFO: Pfl01_5534
PFS: PFLU5976(aldH)
PEN: PSEEN5424(aldH)
PMY: Pmen_0237
PSA: PST_0046
 |
|---|
Reference
Authors
Title
Journal
|
1
Yorifuji, T., Koike, K., Sakurai, T. and Yokoyama, K.
4-Aminobutyraldehyde and 4-guanidinobutyraldehyde dehydrogenases for
arginine degradation in Pseudomonas putida.
Agric. Biol. Chem. 50 (1986) 2009-2016. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.1.54
IUBMB Enzyme Nomenclature: 1.2.1.54
ExPASy - ENZYME nomenclature database: 1.2.1.54
BRENDA, the Enzyme Database: 1.2.1.54
CAS: 56831-75-5 |
|---|
