| Entry |
|
|---|
| Name |
6-oxohexanoate dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
6-oxohexanoate:NADP+ oxidoreductase |
|---|
| Reaction(IUBMB) |
6-oxohexanoate + NADP+ + H2O = adipate + NADPH + 2 H+ [RN:R05099] |
|---|
| Reaction(KEGG) |
R05099
 |
|---|
| Substrate |
6-oxohexanoate [CPD:C06102];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Product |
adipate [CPD:C06104];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
Last step in the cyclohexanol degradation pathway in Acinetobacter
sp. |
|---|
| Pathway |
PATH: ec00930 Caprolactam degradation
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:856571]
Davey JF, Trudgill PW.
The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter
species.
Eur. J. Biochem. 74 (1977) 115-27.
Acinetobacter sp. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:1261]
Donoghue NA, Trudgill PW.
The metabolism of cyclohexanol by Acinetobacter NCIB 9871.
Eur. J. Biochem. 60 (1975) 1-7.
Nocardia globerula |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.1.63
IUBMB Enzyme Nomenclature: 1.2.1.63
ExPASy - ENZYME nomenclature database: 1.2.1.63
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.63
BRENDA, the Enzyme Database: 1.2.1.63
CAS: 62628-29-9 |
|---|
