| Entry |
|
| Name |
salicylaldehyde dehydrogenase |
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
 |
| Sysname |
salicylaldehyde:NAD+ oxidoreductase |
| Reaction(IUBMB) |
salicylaldehyde + NAD+ + H2O = salicylate + NADH + 2 H+ [RN:R02941] |
| Reaction(KEGG) |
R02941
 |
| Substrate |
salicylaldehyde [CPD:C06202];
NAD+ [CPD:C00003];
H2O [CPD:C00001] |
| Product |
salicylate [CPD:C00805];
NADH [CPD:C00004];
H+ [CPD:C00080] |
| Comment |
Involved in the naphthalene degradation pathway in some bacteria. |
| Pathway |
PATH: ec00626 Naphthalene and anthracene degradation
PATH: ec01100 Metabolic pathways |
| Orthology |
KO: K00152 salicylaldehyde dehydrogenase |
| Genes |
BPL: BURPS1106A_A1068(vdh)
BUR: Bcep18194_A5913 Bcep18194_B0051
PNA: Pnap_1022
RLE: pRL120487
BME: BMEI1559 BMEI1560
 |
Reference Authors Title
Journal Organism
|
1 [PMID:1447127]
Eaton RW, Chapman PJ.
Bacterial metabolism of naphthalene: construction and use of
recombinant bacteria to study ring cleavage of
1,2-dihydroxynaphthalene and subsequent reactions.
J. Bacteriol. 174 (1992) 7542-54.
Pseudomonas aeruginosa [GN:pae] |
| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.1.65
IUBMB Enzyme Nomenclature: 1.2.1.65
ExPASy - ENZYME nomenclature database: 1.2.1.65
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.1.65
BRENDA, the Enzyme Database: 1.2.1.65
CAS: 55354-34-2 |