| Entry |
|
|---|
| Name |
indole-3-acetaldehyde oxidase;
indoleacetaldehyde oxidase;
IAAld oxidase;
AO1;
indole-3-acetaldehyde:oxygen oxidoreductase |
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With oxygen as acceptor
 |
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| Sysname |
(indol-3-yl)acetaldehyde:oxygen oxidoreductase |
|---|
| Reaction(IUBMB) |
(indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2
[RN:R02681] |
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| Reaction(KEGG) |
R02681
 |
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| Substrate |
(indol-3-yl)acetaldehyde;
H2O [CPD:C00001];
O2 [CPD:C00007] |
|---|
| Product |
(indol-3-yl)acetate [CPD:C00954];
H2O2 [CPD:C00027] |
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| Cofactor |
FAD [CPD:C00016];
Heme [CPD:C00032];
Molybdenum [CPD:C00150] |
|---|
| Comment |
A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC
1.2.3.1). It has a preference for aldehydes having an indole-ring
structure as substrate [6,7]. It may play a role in plant hormone
biosynthesis as its activity is higher in the auxin-overproducing
mutant, super-root1, than in wild-type Arabidopsis thaliana [7].
While (indol-3-yl)acetaldehyde is the preferred substrate, it also
oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly.
The enzyme from maize contains FAD, iron and molybdenum [4]. |
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| Pathway |
PATH: ec00380 Tryptophan metabolism |
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| Orthology |
KO: K11817 indole-3-acetaldehyde oxidase |
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| Genes |
ATH: AT5G20960(AAO1)
OSA: 4348072(Os10g0138100)
 |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:16660220]
Bower PJ, Brown HM, Purves WK.
Cucumber Seedling Indoleacetaldehyde Oxidase.
Plant. Physiol. 61 (1978) 107-110.
Cucumis sativus |
|---|
Reference
Authors
Title
Journal
|
2
Miyata, S., Suzuki, Y., Kamisaka, S. and Masuda, Y.
Indole-3-acetaldehyde oxidase of pea-seedlings.
Physiol. Plant. 51 (1981) 402-406. |
|---|
Reference
Authors
Title
Journal
|
3
Rajagopal, R.
Metabolism of indole-3-acetaldehyde. III. Some characteristics of
the aldehyde oxidase of Avena coleoptiles.
Physiol. Plant. 24 (1971) 272-281. |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:12226218]
Koshiba T, Saito E, Ono N, Yamamoto N, Sato M.
Purification and Properties of Flavin- and Molybdenum-Containing
Aldehyde Oxidase from Coleoptiles of Maize.
Plant. Physiol. 110 (1996) 781-789.
Zea mays [GN:zma] |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:12231908]
Koshiba T, Matsuyama H.
An in Vitro System of Indole-3-Acetic Acid Formation from Tryptophan
in Maize (Zea mays) Coleoptile Extracts.
Plant. Physiol. 102 (1993) 1319-1324.
Zea mays [GN:zma] |
|---|
Reference
Authors
Title
Journal
Organism
|
6 [PMID:9615466]
Sekimoto H, Seo M, Kawakami N, Komano T, Desloire S, Liotenberg S,
Marion-Poll A, Caboche M, Kamiya Y, Koshiba T.
Molecular cloning and characterization of aldehyde oxidases in
Arabidopsis thaliana.
Plant. Cell. Physiol. 39 (1998) 433-42.
Arabidopsis thaliana [GN:ath] |
|---|
Reference
Authors
Title
Journal
Organism
|
7 [PMID:9489015]
Seo M, Akaba S, Oritani T, Delarue M, Bellini C, Caboche M, Koshiba
T.
Higher activity of an aldehyde oxidase in the auxin-overproducing
superroot1 mutant of Arabidopsis thaliana.
Plant. Physiol. 116 (1998) 687-93.
Arabidopsis thaliana [GN:ath] |
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| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.3.7
IUBMB Enzyme Nomenclature: 1.2.3.7
ExPASy - ENZYME nomenclature database: 1.2.3.7
BRENDA, the Enzyme Database: 1.2.3.7
CAS: 66082-22-2 |
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