KEGG   ENZYME: 1.2.99.7Help
Entry
EC 1.2.99.7                 Enzyme                                 

Name
aldehyde dehydrogenase (FAD-independent);
aldehyde oxidase;
aldehyde oxidoreductase;
Mop;
AORDd
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With other acceptors
BRITE hierarchy
Sysname
aldehyde:acceptor oxidoreductase (FAD-independent)
Reaction(IUBMB)
an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor [RN:R00544]
Reaction(KEGG)
Substrate
aldehyde [CPD:C00071];
H2O [CPD:C00001];
acceptor [CPD:C00028]
Product
carboxylate [CPD:C00060];
reduced acceptor [CPD:C00030]
Comment
Belongs to the xanthine oxidase family of enzymes. The enzyme from Desulfovibrio sp. contains a molybdenum-molybdopterin-cytosine dinucleotide (MCD) complex and two types of [2Fe-2S] cluster per monomer, but does not contain FAD.
History
EC 1.2.99.7 created 2004
Orthology
K07469  
aldehyde oxidoreductase
Genes
SDL: 
SMUL: 
GUR: 
PCA: 
PPD: 
DVU: 
DVU1559(mop)
DVL: 
DVM: 
DVG: 
DDE: 
DDS: 
DDN: 
DMA: 
DSA: 
DAF: 
DHY: 
DPI: 
DGG: 
DBA: 
DRT: 
DPS: 
DPR: 
DAT: 
DTO: 
DTI: 
SFU: 
CLJ: 
CLS: 
CSR: 
CAH: 
RUM: 
ROB: 
DSY: 
DHD: 
DDH: 
DAE: 
DCA: 
DRU: 
DGI: 
PTH: 
DOR: 
DAI: 
DMI: 
AWO: 
OVA: 
STR: 
AMO: 
 » show all
Taxonomy
Reference
1  [PMID:14659539]
  Authors
Uchida H, Kondo D, Yamashita A, Nagaosa Y, Sakurai T, Fujii Y, Fujishiro K, Aisaka K, Uwajima T.
  Title
Purification and characterization of an aldehyde oxidase from Pseudomonas sp. KY 4690.
  Journal
FEMS. Microbiol. Lett. 229 (2003) 31-6.
  Organism
Pseudomonas sp.
Reference
2  [PMID:10679276]
  Authors
Duarte RO, Archer M, Dias JM, Bursakov S, Huber R, Moura I, Romao MJ, Moura JJ.
  Title
Biochemical/spectroscopic characterization and preliminary X-ray analysis of a new aldehyde oxidoreductase isolated from Desulfovibrio desulfuricans ATCC 27774.
  Journal
Biochem. Biophys. Res. Commun. 268 (2000) 745-9.
  Organism
Desulfovibrio desulfuricans
Reference
3  [PMID:10727945]
  Authors
Andrade SL, Brondino CD, Feio MJ, Moura I, Moura JJ.
  Title
Aldehyde oxidoreductase activity in Desulfovibrio alaskensis NCIMB 13491 EPR assignment of the proximal [2Fe-2S] cluster to the Mo site.
  Journal
Eur. J. Biochem. 267 (2000) 2054-61.
  Organism
Desulfovibrio alaskensis
Reference
4  [PMID:7502041]
  Authors
Romao MJ, Archer M, Moura I, Moura JJ, LeGall J, Engh R, Schneider M, Hof P, Huber R.
  Title
Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas.
  Journal
Science. 270 (1995) 1170-6.
  Organism
Desulfovibrio gigas
  Sequence
[dgg:DGI_0902]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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