| Entry |
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| Name |
7-dehydrocholesterol reductase
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| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
cholesterol:NADP+ Delta7-oxidoreductase
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| Reaction(IUBMB) |
cholesterol + NADP+ = cholesta-5,7-dien-3beta-ol + NADPH + H+ [RN: R01456]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Pathway |
| Steroid biosynthesis | | Metabolic pathways | | Biosynthesis of secondary metabolites |
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| Orthology |
| 7-dehydrocholesterol reductase |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | PHU: | | ISC: | | NVE: | | AQU: | | ATH: | | ALY: | | CSV: | | RCU: | | POP: | | VVI: | | OSA: | | DOSA: | | BDI: | | SBI: | | ZMA: | | SMO: | | PPP: | | MGR: | | FGR: | | NHE: | | VAL: | | SSL: | | AOR: | | AFV: | | ACT: | | PCS: | | PBL: | | AJE: | | PTE: | | TML: | | MBR: | | NGR: | | PTI: | | TPS: | | PIF: | | CBU: | | CBS: | | CBD: | | CBC: | | LLO: | | PCU: | | PUV: | | WCH: | |
» show all
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| Reference |
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| Authors |
DEMPSEY ME, SEATON JD, SCHROEPFER GJ Jr, TROCKMAN RW. |
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| Title |
THE INTERMEDIARY ROLE OF DELTA-5,7-CHOLESTADIEN-3-BETA-OL IN CHOLESTEROL BIOSYNTHESIS. |
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| Journal |
J. Biol. Chem. 239 (1964) 1381-7. |
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| Organism |
Rattus norvegicus [GN: rno] |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 9080-21-1 |
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