KEGG   ENZYME: 1.3.1.33Help
Entry
EC 1.3.1.33                 Enzyme                                 
Name
protochlorophyllide reductase;
NADPH2-protochlorophyllide oxidoreductase;
NADPH-protochlorophyllide oxidoreductase;
NADPH-protochlorophyllide reductase;
protochlorophyllide oxidoreductase;
protochlorophyllide photooxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
chlorophyllide-a:NADP+ 7,8-oxidoreductase
Reaction(IUBMB)
chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+ [RN:R03845]
Reaction(KEGG)
R03845;
(other) R06286
Show
Substrate
chlorophyllide a [CPD:C02139];
NADP+ [CPD:C00006]
Product
protochlorophyllide [CPD:C02880];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme catalyses a light-dependent trans-reduction of the D-ring of protochlorophyllide; the product has the (7S,8S)-configuration.
Pathway
Porphyrin and chlorophyll metabolism
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K00218  
protochlorophyllide reductase
Genes
ATH: 
AT1G03630(POR_C) AT4G27440(PORB) AT5G54190(PORA)
ALY: 
GMX: 
CSV: 
RCU: 
POP: 
VVI: 
OSA: 
DOSA: 
Os04t0678700-01(Os04g0678700)
BDI: 
SBI: 
SORBI_01g018230(SORBIDRAFT_01g018230) SORBI_06g033030(SORBIDRAFT_06g033030)
ZMA: 
100194154(pcr1) 100283531 100381341 100381344
SMO: 
SELMODRAFT_150541
PPP: 
PHYPADRAFT_134131(POR2) PHYPADRAFT_217750(POR1)
CRE: 
CHLREDRAFT_136589(POR)
VCN: 
VOLCADRAFT_81013
OLU: 
OSTLU_4180 OSTLU_4520
OTA: 
Ot07g01640
CME: 
CMD190C CMG217C CMN338C
CGR: 
CAGL0J05852g
DHA: 
DEHA2C15202g
PIC: 
PICST_81469(RDH2)
YLI: 
YALI0D09427g
MGR: 
MGG_08430
EHI: 
EHI_158310(242.t00015)
PTI: 
PHATRDRAFT_56608
TPS: 
THAPSDRAFT_25574 THAPSDRAFT_270281
BPM: 
BURPS1710b_A2134
BTE: 
BTH_II1842
BUR: 
Bcep18194_B0618 Bcep18194_C7081
DSH: 
Dshi_4160
BSUB: 
BEST7613_4893(pcr)
SEN: 
SACE_1606 SACE_1627
CWO: 
Cwoe_0924
SYN: 
slr0506(pcr)
SYZ: 
MYO_126430(pcr)
SYY: 
SYNGTS_2618(pcr)
SYT: 
SYNGTI_2617(pcr)
SYS: 
SYNPCCN_2616(pcr)
SYQ: 
SYNPCCP_2616(pcr)
SYW: 
SYNW1129(pcr) SYNW1726(pcr) SYNW2400
SYC: 
syc1603_d(por)
SYF: 
Synpcc7942_2503
SYD: 
Syncc9605_0740 Syncc9605_1268 Syncc9605_2564
SYE: 
Syncc9902_1216 Syncc9902_1623 Syncc9902_2219
SYG: 
sync_1162 sync_1976 sync_2830
SYR: 
SynRCC307_1572(por)
SYX: 
SynWH7803_0669(por) SynWH7803_0868 SynWH7803_2446
SYP: 
SYNPCC7002_A0210(por)
CYA: 
CYA_2383
CYB: 
CYB_1015
SYNE: 
Syn6312_0658
SYNP: 
Syn7502_01296
TEL: 
tlr0575(por)
MAR: 
MAE_13650(por)
CYT: 
cce_0320(por)
CYP: 
PCC8801_3722
CYC: 
PCC7424_4969
CYN: 
Cyan7425_1998
CYH: 
Cyan8802_3774
CYJ: 
Cyan7822_2743
AMR: 
AM1_1191(por)
CAN: 
Cyan10605_0183
CSN: 
Cyast_2878
DSL: 
Dacsa_1706
HAO: 
PCC7418_0447
GLP: 
Glo7428_1451
CMP: 
Cha6605_5745
GVI: 
gvip343(por)
ANA: 
all1743(por)
NPU: 
Npun_R2763
NOS: 
Nos7107_1104
NOP: 
Nos7524_2074
AVA: 
Ava_0294
ANB: 
ANA_C10499(por)
ACY: 
Anacy_0630
NAZ: 
Aazo_0190
CSG: 
Cylst_0301
CALO: 
Cal7507_0929
CALT: 
Cal6303_1239
RIV: 
Riv7116_5568
PMA: 
Pro0543(por) Pro0791(por) Pro1537(por)
PMM: 
PMM0542(por) PMM0634(por) PMM1361
PMT: 
PMT0480 PMT0871(F21B7.35) PMT1218(pcr)
PMN: 
PMN2A_0074 PMN2A_0729
PMI: 
PMT9312_0542 PMT9312_0634
PMB: 
A9601_05981 A9601_06901 A9601_15641
PMC: 
P9515_06061 P9515_07001 P9515_15241
PMF: 
P9303_07921 P9303_13231 P9303_17961
PMG: 
P9301_05681 P9301_06611 P9301_15491
PMH: 
P9215_06231 P9215_07171 P9215_15921
PMJ: 
P9211_05441 P9211_07421 P9211_14681
PME: 
NATL1_05961 NATL1_06971 NATL1_15671
TER: 
Tery_0109
LEP: 
Lepto7376_2250
GEI: 
GEI7407_1773
OAC: 
Oscil6304_5032
ONI: 
Osc7112_5520
PSEU: 
Pse7367_3906
CEP: 
Cri9333_1666
MIC: 
Mic7113_2909
CTHE: 
Chro_4371
PLP: 
Ple7327_2034
SCS: 
Sta7437_3754
 » show all
Taxonomy
Reference
1  [PMID:7439188]
  Authors
Apel K, Santel HJ, Redlinger TE, Falk H.
  Title
The protochlorophyllide holochrome of barley (Hordeum vulgare L.). Isolation and characterization of the NADPH:protochlorophyllide oxidoreductase.
  Journal
Eur. J. Biochem. 111 (1980) 251-8.
  Organism
Hordeum vulgare
Reference
2  [PMID:31865]
  Authors
Griffiths WT.
  Title
Reconstitution of chlorophyllide formation by isolated etioplast membranes.
  Journal
Biochem. J. 174 (1978) 681-92.
  Organism
Hordeum vulgare
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
68518-04-7
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