KEGG   ENZYME: 1.3.1.37Help
Entry
EC 1.3.1.37                 Enzyme                                 

Name
cis-2-enoyl-CoA reductase (NADPH);
NADPH-dependent cis-enoyl-CoA reductase;
reductase, cis-2-enoyl coenzyme A;
cis-2-enoyl-coenzyme A reductase;
cis-2-enoyl-CoA reductase (NADPH)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
acyl-CoA:NADP+ cis-2-oxidoreductase
Reaction(IUBMB)
acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH + H+ [RN:R00387]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
NADP+ [CPD:C00006]
Product
cis-2,3-dehydroacyl-CoA [CPD:C01122];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Not identical with EC 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH) [cf. EC 1.3.1.8 acyl-CoA dehydrogenase (NADP+)].
History
EC 1.3.1.37 created 1986
Reference
1  [PMID:6759504]
  Authors
Mizugaki M, Nishimaki T, Shiraishi T, Kawaguchi A, Okuda S, Yamanaka H.
  Title
Studies on the metabolism of unsaturated fatty acids. IX. Stereochemical studies of the reaction catalyzed by trans-2-enoyl-coenzyme A reductase of Escherichia coli.
  Journal
J. Biochem. (Tokyo). 92 (1982) 1649-54.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
72841-00-0

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