| Entry |
|
|---|
| Name |
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase;
2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase |
|---|
| Reaction(IUBMB) |
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol
+ NADH + H+ [RN:R05239] |
|---|
| Reaction(KEGG) |
R05239;
(other) R05241
 |
|---|
| Substrate |
cis-3-phenylcyclohexa-3,5-diene-1,2-diol [CPD:C06589];
NAD+ [CPD:C00003] |
|---|
| Product |
biphenyl-2,3-diol [CPD:C02526];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Comment |
Catalyses the second step in the biphenyl degradation pathway in
bacteria. |
|---|
| Pathway |
PATH: ec00621 Biphenyl degradation
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K08690 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase |
|---|
| Genes |
BXE: Bxe_C1192(bphB)
PNA: Pnap_4147
RHA: RHA1_ro08054(bphB1)
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:8702262]
Sylvestre M, Hurtubise Y, Barriault D, Bergeron J, Ahmad D.
Characterization of active recombinant
2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas
testosteroni B-356 and sequence of the encoding gene (bphB).
Appl. Environ. Microbiol. 62 (1996) 2710-5.
Comamonas testosteroni |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:8048958]
Fukuda M, Yasukochi Y, Kikuchi Y, Nagata Y, Kimbara K, Horiuchi H,
Takagi M, Yano K.
Identification of the bphA and bphB genes of Pseudomonas sp. strains
KKS102 involved in degradation of biphenyl and polychlorinated
biphenyls.
Biochem. Biophys. Res. Commun. 202 (1994) 850-6.
Pseudomonas sp. |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:8344527]
Hofer B, Eltis LD, Dowling DN, Timmis KN.
Genetic analysis of a Pseudomonas locus encoding a pathway for
biphenyl/polychlorinated biphenyl degradation.
Gene. 130 (1993) 47-55.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.1.56
IUBMB Enzyme Nomenclature: 1.3.1.56
ExPASy - ENZYME nomenclature database: 1.3.1.56
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.56
BRENDA, the Enzyme Database: 1.3.1.56 |
|---|
