| Entry |
|
|---|
| Name |
phthalate 4,5-cis-dihydrodiol dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+
oxidoreductase |
|---|
| Reaction(IUBMB) |
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ =
4,5-dihydroxyphthalate + NADH + H+ [RN:R05275] |
|---|
| Reaction(KEGG) |
R05275
 |
|---|
| Substrate |
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate
[CPD:C04783];
NAD+ [CPD:C00003] |
|---|
| Product |
4,5-dihydroxyphthalate [CPD:C03233];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Comment |
Involved in the phthalate degradation pathway in bacteria. |
|---|
| Pathway |
PATH: ec00623 2,4-Dichlorobenzoate degradation
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3805038]
Batie CJ, LaHaie E, Ballou DP.
Purification and characterization of phthalate oxygenase and
phthalate oxygenase reductase from Pseudomonas cepacia.
J. Biol. Chem. 262 (1987) 1510-8.
Pseudomonas cepacia |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.1.64
IUBMB Enzyme Nomenclature: 1.3.1.64
ExPASy - ENZYME nomenclature database: 1.3.1.64
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.64
BRENDA, the Enzyme Database: 1.3.1.64 |
|---|
