| Entry |
|
| Name |
1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase |
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
 |
| Sysname |
1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+
oxidoreductase (decarboxylating) |
| Reaction(IUBMB) |
1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ =
3-methylcatechol + NADH + CO2 [RN:R05314] |
| Reaction(KEGG) |
R05314
 |
| Substrate |
1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate [CPD:C06731];
NAD+ [CPD:C00003] |
| Product |
3-methylcatechol [CPD:C02923];
NADH [CPD:C00004];
CO2 [CPD:C00011] |
| Comment |
Involved in the o-xylene degradation pathway in bacteria. |
| Pathway |
PATH: ec00622 Toluene and xylene degradation
PATH: ec01100 Metabolic pathways |
Reference Authors Title Journal Organism
|
1 [PMID:1371658]
Higson FK, Focht DD.
Degradation of 2-methylbenzoic acid by Pseudomonas cepacia MB2.
Appl. Environ. Microbiol. 58 (1992) 194-200.
Pseudomonas cepacia |
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.1.68
IUBMB Enzyme Nomenclature: 1.3.1.68
ExPASy - ENZYME nomenclature database: 1.3.1.68
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.68
BRENDA, the Enzyme Database: 1.3.1.68 |