KEGG   ENZYME: 1.3.1.68Help
Entry
EC 1.3.1.68                 Enzyme                                 

Name 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
Class Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+
oxidoreductase (decarboxylating)
Reaction(IUBMB) 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD+ =
3-methylcatechol + NADH + CO2 [RN:R05314]
Reaction(KEGG) R05314
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Substrate 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate [CPD:C06731];
NAD+ [CPD:C00003]
Product 3-methylcatechol [CPD:C02923];
NADH [CPD:C00004];
CO2 [CPD:C00011]
Comment Involved in the o-xylene degradation pathway in bacteria.
Pathway PATH: ec00622  Toluene and xylene degradation
PATH: ec01100  Metabolic pathways
Reference
  Authors
  Title
  Journal
  Organism
1  [PMID:1371658]
Higson FK, Focht DD.
Degradation of 2-methylbenzoic acid by Pseudomonas cepacia MB2.
Appl. Environ. Microbiol. 58 (1992) 194-200.
Pseudomonas cepacia
Other DBs ExplorEnz - The Enzyme Database: 1.3.1.68
IUBMB Enzyme Nomenclature: 1.3.1.68
ExPASy - ENZYME nomenclature database: 1.3.1.68
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.68
BRENDA, the Enzyme Database: 1.3.1.68

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