| Entry |
|
|---|
| Name |
L-galactonolactone oxidase;
L-galactono-1,4-lactone oxidase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With oxygen as acceptor
 |
|---|
| Sysname |
L-galactono-1,4-lactone:oxygen 3-oxidoreductase |
|---|
| Reaction(IUBMB) |
L-galactono-1,4-lactone + O2 = L-ascorbate + H2O2 [RN:R00643] |
|---|
| Reaction(KEGG) |
R00643
 |
|---|
| Substrate |
L-galactono-1,4-lactone [CPD:C01115];
O2 [CPD:C00007] |
|---|
| Product |
L-ascorbate [CPD:C00072];
H2O2 [CPD:C00027] |
|---|
| Cofactor |
FAD [CPD:C00016] |
|---|
| Comment |
A flavoprotein. Acts on the 1,4-lactones of L-galactonic,
D-altronic, L-fuconic, D-arabinic and D-threonic acids; not
identical with EC 1.1.3.8 L-gulonolactone oxidase. (cf. EC 1.3.2.3
galactonolactone dehydrogenase). |
|---|
| Pathway |
PATH: ec00053 Ascorbate and aldarate metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K05276 L-galactonolactone oxidase |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:6754380]
Bleeg HS, Christensen F.
Biosynthesis of ascorbate in yeast. Purification of
L-galactono-1,4-lactone oxidase with properties different from
mammalian L-gulonolactone oxidase.
Eur. J. Biochem. 127 (1982) 391-6.
Saccharomyces cerevisiae [GN:sce] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.3.12
IUBMB Enzyme Nomenclature: 1.3.3.12
ExPASy - ENZYME nomenclature database: 1.3.3.12
BRENDA, the Enzyme Database: 1.3.3.12
CAS: 69403-13-0 |
|---|
