| Entry |
|
|---|
| Name |
long-chain-acyl-CoA dehydrogenase;
palmitoyl-CoA dehydrogenase;
palmitoyl-coenzyme A dehydrogenase;
long-chain acyl-coenzyme A dehydrogenase;
long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With other acceptors
 |
|---|
| Sysname |
long-chain-acyl-CoA:acceptor 2,3-oxidoreductase |
|---|
| Reaction(IUBMB) |
acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor
[RN:R00392] |
|---|
| Reaction(KEGG) |
R00392 > R01279 R03777 R03857 R03990 R04751 R04754
 |
|---|
| Substrate |
acyl-CoA [CPD:C00040];
acceptor [CPD:C00028] |
|---|
| Product |
2,3-dehydroacyl-CoA [CPD:C00605];
reduced acceptor [CPD:C00030] |
|---|
| Cofactor |
FAD [CPD:C00016] |
|---|
| Comment |
A flavoprotein (FAD); forms with another flavoprotein
('electron-transferring flavoprotein') and EC 1.5.5.1 a system
reducing ubiquinone and other acceptors. Not identical with EC
1.3.99.2 (butyryl-CoA dehydrogenase), EC 1.3.99.3 (acyl-CoA
dehydrogenase), EC 1.3.99.10 (isovaleryl-CoA dehydrogenase) or EC
1.3.99.12 (2-methylacyl-CoA dehydrogenase). |
|---|
| Pathway |
PATH: ec00071 Fatty acid metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00255 long-chain-acyl-CoA dehydrogenase |
|---|
| Genes |
HSA: 33(ACADL)
PTR: 459914(ACADL)
MCC: 711485
MMU: 11363(Acadl)
RNO: 25287(Acadl)
CFA: 478895(ACADL)
BTA: 614508(ACADL)
SSC: 396931(ACADL)
ECB: 100066893
MDO: 100015264
OAA: 100077024
GGA: 424005(ACADL)
TGU: 100224317
XLA: 446669(acadl)
XTR: 734116
DRE: 100150734 394156(acadl)
SPU: 577166
PAP: PSPA7_5007
ACI: ACIAD1723(hcaD) ACIAD2226 ACIAD3191(fadE)
ACB: A1S_1108 A1S_2279 A1S_3053
ABM: ABSDF0451(fadE) ABSDF1249
ABY: ABAYE0436(fadE) ABAYE1204 ABAYE2631(hcaD)
BMV: BMASAVP1_A3482
BML: BMA10229_A1825
BMN: BMA10247_2728
BPL: BURPS1106A_0069
BPD: BURPS668_0071
BUR: Bcep18194_C6743 Bcep18194_C6744 Bcep18194_C7184
SAT: SYN_02128
SIL: SPO2380
SIT: TM1040_1559
RDE: RD1_3970(fadE)
NAR: Saro_0132
MAV: MAV_1822 MAV_1883 MAV_2561 MAV_3616 MAV_4768
MSM: MSMEG_5197
MUL: MUL_3367(fadE20)
MVA: Mvan_2439
RHA: RHA1_ro00550 RHA1_ro02345 RHA1_ro02627 RHA1_ro02715
RHA1_ro02754 RHA1_ro03954 RHA1_ro05132 RHA1_ro06787
RHA1_ro08138
RSA: RSal33209_2142
FAL: FRAAL0412 FRAAL2362 FRAAL2625 FRAAL3144 FRAAL4870
SEN: SACE_3993 SACE_6369
RRS: RoseRS_2850
RCA: Rcas_2461
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:1015826]
Hall CL, Heijkenskjold L, Bartfai T, Ernster L, Kamin H.
Acyl coenzyme A dehydrogenases and electron-transferring
flavoprotein from beef hart mitochondria.
Arch. Biochem. Biophys. 177 (1976) 402-14.
Bos taurus [GN:bta] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13319294]
HAUGE JG, CRANE FL, BEINERT H.
On the mechanism of dehydrogenation of fatty acyl derivatives of
coenzyme A. III. Palmityl coA dehydrogenase.
J. Biol. Chem. 219 (1956) 727-33.
Sus scofa [GN:ssc] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:3968063]
Ikeda Y, Okamura-Ikeda K, Tanaka K.
Purification and characterization of short-chain, medium-chain, and
long-chain acyl-CoA dehydrogenases from rat liver mitochondria.
Isolation of the holo- and apoenzymes and conversion of the
apoenzyme to the holoenzyme.
J. Biol. Chem. 260 (1985) 1311-25.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.99.13
IUBMB Enzyme Nomenclature: 1.3.99.13
ExPASy - ENZYME nomenclature database: 1.3.99.13
BRENDA, the Enzyme Database: 1.3.99.13
CAS: 59536-74-2 |
|---|
