| Entry |
|
|---|
| Name |
butyryl-CoA dehydrogenase;
butyryl dehydrogenase;
unsaturated acyl-CoA reductase;
ethylene reductase;
enoyl-coenzyme A reductase;
unsaturated acyl coenzyme A reductase;
butyryl coenzyme A dehydrogenase;
short-chain acyl CoA dehydrogenase;
short-chain acyl-coenzyme A dehydrogenase;
3-hydroxyacyl CoA reductase;
butanoyl-CoA:(acceptor) 2,3-oxidoreductase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With other acceptors
 |
|---|
| Sysname |
butanoyl-CoA:acceptor 2,3-oxidoreductase |
|---|
| Reaction(IUBMB) |
butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor
[RN:R01178] |
|---|
| Reaction(KEGG) |
R01178 > R01175;
(other) R01171 R02661 R03172 R04751
 |
|---|
| Substrate |
butanoyl-CoA [CPD:C00136];
acceptor [CPD:C00028] |
|---|
| Product |
2-butenoyl-CoA [CPD:C00877];
reduced acceptor [CPD:C00030] |
|---|
| Cofactor |
FAD [CPD:C00016] |
|---|
| Comment |
A flavoprotein; forms, with another flavoprotein
('electron-transferring flavoproteins') and EC 1.5.5.1
electron-transferring-flavoprotein dehydrogenase, a system reducing
ubiquinone and other acceptors. |
|---|
| Pathway |
PATH: ec00071 Fatty acid metabolism
PATH: ec00280 Valine, leucine and isoleucine degradation
PATH: ec00650 Butanoate metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00248 butyryl-CoA dehydrogenase |
|---|
| Genes |
HSA: 35(ACADS)
PTR: 742921(ACADS)
MCC: 698196(ACADS)
MMU: 11409(Acads)
RNO: 64304(Acads)
CFA: 477517(ACADS)
BTA: 511222(ACADS)
SSC: 396932(ACADS)
ECB: 100147113
MDO: 100025804
OAA: 100090404
GGA: 416969(ACADS)
TGU: 100232428
XLA: 380563(acads)
XTR: 394882(acads)
DRE: 445288(acads)
CIN: 100175610
SPU: 579817
DME: Dmel_CG4703(Arc42)
DPO: Dpse_GA18369(Dpse_Arc42)
AAG: AaeL_AAEL004137
AME: 411697
TCA: 661684
NVE: NEMVE_v1g179716
MBR: MONBRDRAFT_34864
PAE: PA5020
PAU: PA14_66350
PPU: PP_4948
PPF: Pput_4821
PST: PSPTO_5020
PSB: Psyr_0505
PSP: PSPPH_0495 PSPPH_3615
PFL: PFL_0494
PFO: Pfl01_0451
PEN: PSEEN5004
PMY: Pmen_0561
PSA: PST_3878
PCR: Pcryo_0861 Pcryo_1516
PRW: PsycPRwf_1004
ACI: ACIAD1412
SDN: Sden_1941
SFR: Sfri_1340 Sfri_2066
SAZ: Sama_1377
SBL: Sbal_1497
SLO: Shew_1669 Shew_2868
SSE: Ssed_1475
PHA: PSHAa0907 PSHAa1456 PSHAa1920(fadE)
PAT: Patl_0949 Patl_2141
MAQ: Maqu_2132 Maqu_2845
LPN: lpg0868
LPF: lpl0900
LPP: lpp0931
NOC: Noc_1555
ABO: ABO_0833 ABO_1918(acdS)
RSO: RSc1762
RPI: Rpic_1444
RPF: Rpic12D_1485
REU: Reut_A1408 Reut_B3825 Reut_B4150 Reut_B4257 Reut_C6425
REH: H16_A0172 H16_B0752 H16_B0850
RME: Rmet_1852
BUR: Bcep18194_A4177 Bcep18194_A6048 Bcep18194_B0714 Bcep18194_B1438
Bcep18194_B1754 Bcep18194_B2643 Bcep18194_C6872 Bcep18194_C7290
Bcep18194_C7492
RFR: Rfer_2384 Rfer_4169 Rfer_4181
POL: Bpro_2570
AAV: Aave_2602 Aave_2877
AJS: Ajs_1687
VEI: Veis_1790 Veis_3538
MPT: Mpe_A1777
HAR: HEAR0621 HEAR2838(acdB)
GME: Gmet_1715
GUR: Gura_3040
BBA: Bd1973
ADE: Adeh_0360 Adeh_1647 Adeh_1664 Adeh_1665
MXA: MXAN_0797
SAT: SYN_00480 SYN_02587
SFU: Sfum_1371
BME: BMEI0689 BMEII0818
BMF: BAB1_1333
BMB: BruAb1_1314
BJA: bll3855 bll5455 blr3437 blr3448 blr3955
BRA: BRADO2179 BRADO2575 BRADO3035
BBT: BBta_2498 BBta_2922 BBta_3103
RPE: RPE_3222
NWI: Nwi_2158
NHA: Nham_2558
MEX: Mext_4104
SIT: TM1040_2796
RSP: RSP_0156
JAN: Jann_1909
RDE: RD1_1713 RD1_3681(acdA)
PDE: Pden_0714
NAR: Saro_0858
ACR: Acry_1573
RRU: Rru_A1308 Rru_A1835
BCZ: BCZK5042(mmgC)
BTK: BT9727_5025 BT9727_5026(mmgC)
BTL: BALH_4840(acdA) BALH_4841(acd)
BCL: ABC1506
OIH: OB1695
EAT: EAT1b_0815
LBR: LVIS_1909
CAC: CAC2711(bcd)
CPE: CPE2300(bcd)
CPF: CPF_0092 CPF_2584(bcd)
CPR: CPR_2286(bcd)
CTC: CTC00710 CTC01387
CNO: NT01CX_0473
CDF: CD0399(acdB) CD1054(bcd2)
CBO: CBO3199(bcd)
CBK: CLL_A0374
CBT: CLH_0362
CBE: Cbei_0322
CKL: CKL_0455(bcd)
SWO: Swol_0268 Swol_0488 Swol_0788 Swol_1483 Swol_1841
DSY: DSY1568
DRM: Dred_0402 Dred_1490 Dred_1782
PTH: PTH_0015(caiA)
TTE: TTE0545(caiA)
CHY: CHY_1323(bcd1) CHY_1350(bcd2) CHY_1602(bcd3)
MAV: MAV_2590 MAV_5068
MVA: Mvan_0221 Mvan_1977
MGI: Mflv_0446 Mflv_4367 Mflv_4743
MMC: Mmcs_0182
MKM: Mkms_0191
MJL: Mjls_0171
NFA: nfa24470(fadE24)
RHA: RHA1_ro02521 RHA1_ro03348 RHA1_ro03612 RHA1_ro03878
RHA1_ro05203 RHA1_ro06400
NCA: Noca_3506
TFU: Tfu_0946 Tfu_1281
FRA: Francci3_1549 Francci3_2167 Francci3_2247 Francci3_2419
FAL: FRAAL2792(acd) FRAAL3384 FRAAL6072
ACE: Acel_0405
RXY: Rxyl_1707
ABA: Acid345_1131 Acid345_2471
SUS: Acid_5310
CHU: CHU_3827(bcd)
FNU: FN1424 FN1535
DRA: DR_A0250
DGE: Dgeo_2405
TTH: TTC0238 TTC1575
TTJ: TTHA1938 TTHB022
TLE: Tlet_1831
TME: Tmel_0656
FNO: Fnod_0585
PTO: PTO1025 PTO1396
PIS: Pisl_1436
PCL: Pcal_0838
PAS: Pars_0456
 |
|---|
| Structures |
PDB: 1BUC 1JQI 2VIG |
|---|
Reference
Authors
Title
Journal
|
1
Beinert, H.
Acyl coenzyme A dehydrogenase.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 7, Academic Press, New York, 1963, p. 447-466. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13201608]
MAHLER HR, MACKLER B, GREEN DE.
Studies on metalloflavoproteins. III. Aldehyde oxidase: a
molybdoflavoprotein.
J. Biol. Chem. 210 (1954) 465-80.
Bos taurus [GN:bta] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:13319294]
HAUGE JG, CRANE FL, BEINERT H.
On the mechanism of dehydrogenation of fatty acyl derivatives of
coenzyme A. III. Palmityl coA dehydrogenase.
J. Biol. Chem. 219 (1956) 727-33.
Sus scofa [GN:ssc] |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:13130522]
MAHLER HR.
Studies on the fatty acid oxidizing system of animal tissues. IV.
The prosthetic group of butyryl coenzyme A dehydrogenase.
J. Biol. Chem. 206 (1954) 13-26.
Bos taurus [GN:bta] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.99.2
IUBMB Enzyme Nomenclature: 1.3.99.2
ExPASy - ENZYME nomenclature database: 1.3.99.2
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.99.2
BRENDA, the Enzyme Database: 1.3.99.2
CAS: 9027-88-7 |
|---|
