KEGG   ENZYME: 1.3.99.6Help
Entry
EC 1.3.99.6                 Enzyme                                 

Name
3-oxo-5beta-steroid 4-dehydrogenase;
3-oxo-5beta-steroid:(acceptor) Delta4-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With other, unknown, acceptors
BRITE hierarchy
Sysname
3-oxo-5beta-steroid:acceptor Delta4-oxidoreductase
Reaction(IUBMB)
a 3-oxo-5beta-steroid + acceptor = a 3-oxo-Delta4-steroid + reduced acceptor [RN:R02642]
Reaction(KEGG)
R02642 > R02215;
(other) R02219
Show
Substrate
3-oxo-5beta-steroid [CPD:C02797];
acceptor [CPD:C00028]
Product
3-oxo-Delta4-steroid [CPD:C00619];
reduced acceptor [CPD:C00030]
History
EC 1.3.99.6 created 1972
Pathway
Steroid hormone biosynthesis
Metabolic pathways
Reference
1  [PMID:5907467]
  Authors
Davidson SJ, Talalay P.
  Title
Purification and mechanism of action of a steroid delta-4-5-beta-dehydrogenase.
  Journal
J. Biol. Chem. 241 (1966) 906-15.
  Organism
Comamonas testosteroni
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9067-97-4

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