| Entry |
|
|---|
| Name |
diaminopimelate dehydrogenase;
meso-alpha,epsilon-diaminopimelate dehydrogenase;
meso-diaminopimelate dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating) |
|---|
| Reaction(IUBMB) |
meso-2,6-diaminoheptanedioate + H2O + NADP+ =
L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+ [RN:R02755] |
|---|
| Reaction(KEGG) |
R02755
 |
|---|
| Substrate |
meso-2,6-diaminoheptanedioate [CPD:C00680];
H2O [CPD:C00001];
NADP+ [CPD:C00006] |
|---|
| Product |
L-2-amino-6-oxoheptanedioate [CPD:C03871];
NH3 [CPD:C00014];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Pathway |
PATH: ec00300 Lysine biosynthesis |
|---|
| Orthology |
KO: K03340 diaminopimelate dehydrogenase |
|---|
| Genes |
PMR: PMI0150
PRW: PsycPRwf_0683
TGR: Tgr7_1592
RFR: Rfer_1518
AJS: Ajs_2757
DAC: Daci_2479
DIA: Dtpsy_2247
CTT: CtCNB1_3320
HAR: HEAR2481
CCO: CCC13826_1251
PCA: Pcar_2787
DDS: Ddes_1119
GYM: GYMC10_4995
LSP: Bsph_3035
CTC: CTC02532
CNO: NT01CX_0433
CTH: Cthe_0922
CBK: CLL_A3000
CBT: CLH_2749
CPY: Cphy_2659
CCE: Ccel_2533
STH: STH1425
SWO: Swol_0940
VPR: Vpar_0329
DSY: DSY0242
DHD: Dhaf_0187
ACL: ACL_0763
CGL: NCgl2528(cgl2617)
CGB: cg2900(ddh)
CGT: cgR_2525
CEF: CE2498(ddh)
CUR: cur_1936(ddh)
MLU: Mlut_19060
BFA: Bfae_19670
CCU: Ccur_13630
ELE: Elen_0753
BTH: BT_1979
BFR: BF3690
BFS: BF3481
BVU: BVU_1659
PGI: PG0806
PGN: PGN_0830
PDI: BDI_3565
FSU: Fisuc_0002
OTE: Oter_4154
AMU: Amuc_0581
EMI: Emin_1048
MVN: Mevan_0344
 |
|---|
| Structures |
PDB: 1DAP 1F06 2DAP 3DAP |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:10904]
Misono H, Togawa H, Yamamoto T, Soda K.
Occurrence of meso-alpha, epsilon-diaminopimelate dehydrogenase in
Bacillus sphaericus.
Biochem. Biophys. Res. Commun. 72 (1976) 89-93.
Bacillus sphaericus |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:762012]
Misono H, Togawa H, Yamamoto T, Soda K.
Meso-alpha,epsilon-diaminopimelate D-dehydrogenase: distribution and
the reaction product.
J. Bacteriol. 137 (1979) 22-7.
Corynebacterium glutamicum [GN:cgl cgb], Bacillus sphaericus,
Brevibacterium sp., Proteus vulgaris |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.4.1.16
IUBMB Enzyme Nomenclature: 1.4.1.16
ExPASy - ENZYME nomenclature database: 1.4.1.16
BRENDA, the Enzyme Database: 1.4.1.16
CAS: 60894-21-5 |
|---|
