| Entry |
|
|---|
| Name |
1-pyrroline-5-carboxylate dehydrogenase;
Delta1-pyrroline-5-carboxylate dehydrogenase;
1-pyrroline dehydrogenase;
pyrroline-5-carboxylate dehydrogenase;
pyrroline-5-carboxylic acid dehydrogenase;
L-pyrroline-5-carboxylate-NAD+ oxidoreductase;
1-pyrroline-5-carboxylate:NAD+ oxidoreductase;
Delta1-pyrroline-5-carboxylic acid dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
(S)-1-pyrroline-5-carboxylate:NAD+ oxidoreductase |
|---|
| Reaction(IUBMB) |
(S)-1-pyrroline-5-carboxylate + NAD(P)+ + 2 H2O = L-glutamate +
NAD(P)H + H+ [RN:R00707 R00708] |
|---|
| Reaction(KEGG) |
R00707 R00708;
(other) R00245 R04444 R04445 R05051
 |
|---|
| Substrate |
(S)-1-pyrroline-5-carboxylate [CPD:C03912];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Product |
L-glutamate [CPD:C00025];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
This enzyme can oxidize a number of 1-pyrrolines, e.g.
3-hydroxy-1-pyrroline-5-carboxylate is converted into
4-hydroxyglutamate and (R)-1-pyrroline-5-carboxylate is converted
into D-glutamate. While NAD+ appears to be the better electron
acceptor, NADP+ can also act, but more slowly [1,3]. In many
organisms, ranging from bacteria to mammals, proline is oxidized to
glutamate in a two-step process involving this enzyme and EC
1.5.99.8, proline dehydrogenase [3]. In many bacterial species, both
activities are carried out by a single bifunctional enzyme [3,4]. |
|---|
| Pathway |
PATH: ec00250 Alanine, aspartate and glutamate metabolism
PATH: ec00330 Arginine and proline metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00294 1-pyrroline-5-carboxylate dehydrogenase |
|---|
| Genes |
HSA: 8659(ALDH4A1)
MMU: 212647(Aldh4a1)
RNO: 641316
CFA: 612452(ALDH4A1)
BTA: 100126042(ALDH4A1)
ECB: 100147246
OAA: 100085911 100092834
GGA: 419467(ALDH4A1)
TGU: 100220354
XLA: 100036784(aldh4a1)
XTR: 100124732(aldh4a1)
DRE: 394133(aldh4a1)
BFO: BRAFLDRAFT_214534
CIN: 100179556
SPU: 576807
DME: Dmel_CG6661 Dmel_CG7145
DPO: Dpse_GA20135
DAN: Dana_GF23503
DER: Dere_GG13195
DPE: Dper_GL25324
DSE: Dsec_GM22106
DSI: Dsim_GD17558
DYA: Dyak_GE19517
DGR: Dgri_GH17138
DMO: Dmoj_GI11746
AGA: AgaP_AGAP004366
AAG: AaeL_AAEL005422
CQU: CpipJ_CPIJ007660
AME: 551113
NVI: 100116896
TCA: 657887
API: 100165747
ISC: IscW_ISCW015982
CEL: F56D12.1(alh-6)
CBR: CBG07110
BMY: Bm1_04205
SMM: Smp_065060
NVE: NEMVE_v1g186547
HMG: 100211627
TAD: TRIADDRAFT_26837
ATH: AT5G62530
POP: POPTR_581353
RCU: RCOM_1513940
VVI: 100251938
OSA: 4339448(Os05g0536400)
SBI: SORBI_09g026810(SORBIDRAFT_09g026810)
PPP: PHYPADRAFT_207743(ALDH12A)
CRE: CHLREDRAFT_150809(ALD1)
OLU: OSTLU_30910
CME: CMG200C
SCE: YHR037W(PUT2)
AGO: AGOS_AAL071C
KLA: KLLA0C10549g
LTH: KLTH0G06226g
DHA: DEHA0G21769g
PIC: PICST_55391(PUT2)
PPA: PAS_chr2-2_0496
VPO: Kpol_1023p49
LEL: LELG_03981
ZRO: ZYRO0G16874g
CAL: CaO19.11457(PUT2) CaO19.3974(PUT2)
CTP: CTRG_06088
CDU: CD36_54480
CGR: CAGL0D03982g
YLI: YALI0B09647g
SPO: SPBC24C6.04
NCR: NCU03076
PAN: PODANSg5887
MGR: MGG_00189
FGR: FG01141.1
ANI: AN1733.2
AFM: AFUA_6G08750
AOR: AO090001000549
ANG: An02g02290 An11g06140
AFV: AFLA_018620 AFLA_128530
PCS: Pc12g08900 Pc21g19920
NFI: NFIA_054400
CIM: CIMG_06927
URE: UREG_05921
SSL: SS1G_01099
BFU: BC1G_12887
CNE: CNH02450
CNB: CNBL2470
LBC: LACBIDRAFT_188701
MPR: MPER_10681
UMA: UM01250.1
MGL: MGL_2090
MBR: MONBRDRAFT_32088
DDI: DDB_0229934
TGO: TGME49_088450
TET: TTHERM_00822160
PTM: GSPATT00008519001 GSPATT00010303001 GSPATT00012906001
TBR: Tb10.70.4280
TCR: 510943.50
LMA: LmjF03.0200
LIF: LinJ03.0050
LBZ: LbrM03_V2.0210
PTI: PHATRDRAFT_31906
TPS: THAPS_38066(ALD2)
ECO: b1014(putA)
ECJ: JW0999(putA)
ECD: ECDH10B_1086(putA)
EBW: BWG_0868(putA)
ECE: Z1513(putA)
ECS: ECs1260(putA)
ECF: ECH74115_1251(putA)
ETW: ECSP_1183(putA)
ECG: E2348C_1065(putA)
ECC: c1151(putA)
ECI: UTI89_C1077(putA)
ECP: ECP_1013(putA)
ECV: APECO1_105(putA)
ECW: EcE24377A_1132(putA)
ECX: EcHS_A1129(putA)
ECM: EcSMS35_2111(putA)
ECY: ECSE_1076(putA)
ECL: EcolC_2581(putA)
ECK: EC55989_1125(putA)
ECQ: ECED1_1170(putA)
ECR: ECIAI1_1059(putA)
ECT: ECIAI39_2141(putA)
ECZ: ECS88_1030(putA)
EUM: ECUMN_1197(putA)
ELF: LF82_1787(putA)
EBL: B21_01024(putA)
EBD: ECBD_2580
EBR: ECB_01017(putA)
EOH: ECO103_1060(putA)
EOI: ECO111_1203(putA)
EOJ: ECO26_1252(putA)
EFE: EFER_1913(putA)
STY: STY1159(putA)
STT: t1797(putA)
SPT: SPA1727(putA)
SEK: SSPA1605(putA)
SPQ: SPAB_02423(putA)
SEI: SPC_2625(putA)
SEC: SC1074(putA)
SEH: SeHA_C1233(putA)
SEE: SNSL254_A1218(putA)
SEW: SeSA_A1188(putA)
SEA: SeAg_B1083(putA)
SED: SeD_A1198(putA)
SEG: SG1012(putA)
SET: SEN0986A(putA)
SES: SARI_01878(putA)
STM: STM1124(putA)
YPE: YPO1851(putA)
YPK: y2455(putA)
YPM: YP_1542(putA)
YPA: YPA_1229(putA)
YPN: YPN_2272(putA)
YPG: YpAngola_A2037(putA)
YPP: YPDSF_1274(putA)
YPS: YPTB1723(putA)
YPI: YpsIP31758_2268(putA)
YPY: YPK_2369(putA)
YPB: YPTS_1854(putA)
YEN: YE1933(putA)
SSN: SSON_1034(putA)
SBO: SBO_2043(putA)
SBC: SbBS512_E2304(putA)
ECA: ECA4217(putA)
PCT: PC1_4017
PWA: Pecwa_4209
ETA: ETA_14300(putA)
PLU: plu1957(putA)
PAY: PAU_02606(putA)
WBR: WGLp434(putA)
SGL: SG1243(putA)
ENT: Ent638_1541(putA)
ESA: ESA_02357(putA)
CTU: Ctu_15970(putA)
KPN: KPN_01041(putA)
KPE: KPK_3517(putA)
KPU: KP1_2030(putA)
CKO: CKO_02042(putA)
SPE: Spro_2931(putA)
PMR: PMI1616(putA)
EIC: NT01EI_2124
ETR: ETAE_1658(putA)
HDE: HDEF_1208(putA)
DDA: Dd703_3765
DDC: Dd586_3907
DZE: Dd1591_0149
HAP: HAPS_1340(putA)
PMU: PM0589(putA)
APL: APL_0106(putA)
APJ: APJL_0107(putA)
APA: APP7_0106
XCC: XCC3835(putA)
XCB: XC_3907
XCA: xccb100_4021
XCV: XCV4008(putA)
XAC: XAC3890(putA)
XOO: XOO4145(putA)
XOM: XOO_3922
XOP: PXO_04017
SML: Smlt0426(putA)
SMT: Smal_0308
VCO: VC0395_0169(putA)
VCM: VCM66_A1031(putA)
VCJ: VCD_000269
VVU: VV2_1118
VVY: VVA1644
VPA: VPA1726
VHA: VIBHAR_07096
VSP: VS_II0019
VEX: VEA_001017
VFI: VF_A0832(putA)
VFM: VFMJ11_A0958
VSA: VSAL_II0819(putA)
PPR: PBPRB1999
PAE: PA0782(putA)
PAU: PA14_54170(putA)
PAP: PSPA7_4737(putA)
PAG: PLES_45611(putA)
PPU: PP_4947(putA)
PPF: Pput_4819
PPG: PputGB1_4996(putA)
PPW: PputW619_0521(putA)
PST: PSPTO_5017
PSB: Psyr_0506(putA)
PSP: PSPPH_0496(putA)
PFL: PFL_0495(putA)
PFO: Pfl01_0452(putA)
PFS: PFLU0451(putA)
PEN: PSEEN4999(putA)
PMY: Pmen_1110(putA)
PSA: PST_1242(putA)
AVN: Avin_13950(putA)
PAR: Psyc_1249
PCR: Pcryo_1138
PRW: PsycPRwf_1564
ACI: ACIAD1646(putA)
ACB: A1S_1528
ABM: ABSDF2109(putA)
ABY: ABAYE2108(putA)
ABC: ACICU_01574
ABN: AB57_1770
ABB: ABBFA_001949
SON: SO_3774
SDN: Sden_0689
SFR: Sfri_0568
SAZ: Sama_2676
SBL: Sbal_3458
SBM: Shew185_0880
SBN: Sbal195_0913
SBP: Sbal223_0904
SLO: Shew_0615
SPC: Sputcn32_3099
SSE: Ssed_3846
SPL: Spea_3490
SHE: Shewmr4_3122
SHM: Shewmr7_0850
SHN: Shewana3_0819
SHW: Sputw3181_0845
SHL: Shal_3585
SWD: Swoo_0714
SWP: swp_0809
ILO: IL1961(putA)
CPS: CPS_4410(putA)
PHA: PSHAa2264(putA)
PAT: Patl_2218
MAQ: Maqu_2049
AMC: MADE_03716
PIN: Ping_0300 Ping_1543
CBU: CBU_0629(putA)
CBS: COXBURSA331_A0744(putA)
CBD: CBUD_0641(putA)
CBG: CbuG_1374(putA)
CBC: CbuK_1626(putA)
LPN: lpg1696(putA)
LPF: lpl1655(putA)
LPP: lpp1661(putA)
LPC: LPC_1125(putA)
FTU: FTT_1150c(putA)
FTF: FTF1150c(putA)
FTW: FTW_1189(putA)
FTL: FTL_0805
FTH: FTH_0799(putA)
FTA: FTA_0851(putA)
FTM: FTM_0838(putA)
FTN: FTN_1131(putA)
FPH: Fphi_1907
NOC: Noc_1705
AEH: Mlg_2702
HHA: Hhal_0555
HCH: HCH_01824(putA)
CSA: Csal_1249
MMW: Mmwyl1_4428
AHA: AHA_0776
ASA: ASA_0767(putA)
CRP: CRP_077
KKO: Kkor_2154
NMA: NMA2084(putA)
NME: NMB0401(putA)
NMC: NMC1766(putA)
NMN: NMCC_1744(putA)
NMI: NMO_1638(putA)
NGK: NGK_1846
CVI: CV_1538(putA)
LHK: LHK_01861(putA)
RSO: RSc3301(putA)
RPI: Rpic_3496(putA)
RPF: Rpic12D_3171
REU: Reut_A3340(putA)
REH: H16_A3631(putA)
RME: Rmet_3489(putA)
CTI: RALTA_A3086(putA)
BMA: BMA2965(putA)
BMV: BMASAVP1_A3345(putA)
BML: BMA10229_A1576(putA)
BMN: BMA10247_3026(putA)
BPS: BPSL3389(putA)
BPM: BURPS1710b_0166(putA)
BPL: BURPS1106A_4032(putA)
BPD: BURPS668_3958(putA)
BPR: GBP346_A4132
BTE: BTH_I3301(putA)
BVI: Bcep1808_0122(putA)
BUR: Bcep18194_A3294(putA)
BCN: Bcen_2942(putA)
BCH: Bcen2424_0113(putA)
BCM: Bcenmc03_0128(putA)
BCJ: BCAL0042(putA)
BAM: Bamb_0103(putA)
BAC: BamMC406_0112(putA)
BMU: Bmul_0114(putA)
BMJ: BMULJ_03152(putA)
BXE: Bxe_A0049(putA)
BPH: Bphy_3018(putA)
BPY: Bphyt_3887(putA)
BGL: bglu_1g00850
BPE: BP0429 BP2749(putA)
BPA: BPP2579(putA)
BBR: BB2024(putA)
BPT: Bpet2655(putA)
BAV: BAV2084(putA)
RFR: Rfer_2811(putA)
POL: Bpro_0406
PNA: Pnap_4070(putA)
AAV: Aave_3321
AJS: Ajs_2420
VEI: Veis_4442 Veis_4685
DAC: Daci_5941(putA)
DIA: Dtpsy_1427
VAP: Vapar_4810
CTT: CtCNB1_3066 CtCNB1_3067
MPT: Mpe_A3747 Mpe_A3748
HAR: HEAR2142(putA)
MMS: mma_1319(putA)
LCH: Lcho_1628
NET: Neut_1859
NMU: Nmul_A1546
EBA: ebA551(putA)
AZO: azo3753(putA)
TMZ: Tmz1t_0570
APP: CAP2UW1_2548
HPY: HP0056
HPJ: jhp0048(putA)
HPA: HPAG1_0053
HPS: HPSH_00275
HPG: HPG27_51
HPP: HPP12_0050(putA)
HPB: HELPY_0049(putA)
HHE: HH0156
HAC: Hac_1557(putA)
TDN: Suden_1327
CJE: Cj1503c(putA)
CJR: CJE1676
CJJ: CJJ81176_1495
CJU: C8J_1406
CJD: JJD26997_1855
CFF: CFF8240_1241
CLA: Cla_0363(putA)
GSU: GSU3395(putA)
GME: Gmet_3512
GUR: Gura_1871
GBM: Gbem_2411
GEO: Geob_2608
GEM: GM21_1806
PPD: Ppro_0074
DVU: DVU3319(putA)
DVL: Dvul_0070
DVM: DvMF_2146
DDE: Dde_0054
DMA: DMR_43710(putA)
DSA: Desal_1224
DBA: Dbac_3209
DRT: Dret_1959
BBA: Bd1251(putA)
DPS: DP2491
DAL: Dalk_3943
DAT: HRM2_16880(putA2)
ADE: Adeh_0831
ACP: A2cp1_0881
AFW: Anae109_0887
ANK: AnaeK_0877
MXA: MXAN_5891(pruA)
SCL: sce4459(rocA)
HOH: Hoch_0264
SFU: Sfum_0833 Sfum_2203
WOL: WD0103(putA)
WBM: Wbm0539
WRI: WRi_001480(putA)
WPI: WPa_1090(putA)
AMA: AM583(putA)
AMF: AMF_435(putA)
ACN: ACIS_00730(putA)
APH: APH_0669(putA)
ERU: Erum3850(putA)
ERW: ERWE_CDS_03970(putA)
ERG: ERGA_CDS_03930(putA)
ECN: Ecaj_0375
ECH: ECH_0667(putA)
MLO: mll1160
MES: Meso_1325
SME: SMc02181(putA)
SMD: Smed_0092
ATU: Atu4157(putA)
ATC: AGR_L_1394
ARA: Arad_9603(putA)
AVI: Avi_4322
RET: RHE_PF00384(putA)
REC: RHECIAT_PC0000563(putA)
RLE: pRL120554(putA)
RLT: Rleg2_5295
RLG: Rleg_4858
RHI: NGR_c00980(putA1) NGR_c20320(putA2)
BME: BMEII0564
BMI: BMEA_B0697
BMF: BAB2_0518
BMB: BruAb2_0509
BMC: BAbS19_II04880
BMT: BSUIS_B0711
BCS: BCAN_B0728
BMR: BMI_II715
OAN: Oant_3846
BJA: blr7261(putA)
BRA: BRADO6914(putA)
BBT: BBta_6002(putA)
RPA: RPA1580(putA)
RPB: RPB_3946
RPC: RPC_4274
RPD: RPD_3707
RPE: RPE_4317
RPT: Rpal_1768
NWI: Nwi_3055
NHA: Nham_3398
OCA: OCAR_6758
XAU: Xaut_3449
AZC: AZC_0031
MEX: Mext_0319
MEA: Mex_1p0211(putA)
MDI: METDI0194(putA)
MRD: Mrad2831_3056
MET: M446_2202
MPO: Mpop_0395
MCH: Mchl_0364
MNO: Mnod_1441
BID: Bind_2812
MSL: Msil_1659
CCR: CC_0804
CCS: CCNA_00846
CAK: Caul_1044
PZU: PHZ_c0339(putA)
SIL: SPO3010(putA)
SIT: TM1040_1695
RSP: RSP_2166(putA)
RSH: Rsph17029_0838
RSQ: Rsph17025_2326
RSK: RSKD131_0476
JAN: Jann_3494
RDE: RD1_2509(putA)
PDE: Pden_0943
DSH: Dshi_2311(putA)
MMR: Mmar10_0398
HNE: HNE_2333(pruA) HNE_2988
HBA: Hbal_1625
NAR: Saro_0704
SAL: Sala_2773
SWI: Swit_1114
ELI: ELI_11465
GOX: GOX2117
GBE: GbCGDNIH1_0110
ACR: Acry_1039
GDI: GDI_2670(putA)
GDJ: Gdia_0883
APT: APA01_07050
RRU: Rru_A0656
RCE: RC1_1781(putA)
MAG: amb2507
BSU: BSU03210(ycgN) BSU37780(rocA)
BHA: BH2737 BH3940
BAN: BA0309
BAR: GBAA0309
BAA: BA_0880 BA_0884
BAT: BAS0295
BAH: BAMEG_0366
BAI: BAA_0363
BCE: BC0344
BCA: BCE_0338
BCZ: BCZK0282(rocA)
BCR: BCAH187_A0381
BCB: BCB4264_A0355
BCU: BCAH820_0340
BCG: BCG9842_B4965
BCQ: BCQ_0360(rocA)
BCX: BCA_0382
BCY: Bcer98_0289
BTK: BT9727_0279(rocA)
BTL: BALH_0301(rocA)
BWE: BcerKBAB4_0290
BLI: BL01710(ycgN)
BLD: BLi00374(ycgN)
BCL: ABC0965
BAY: RBAM_003450(ycgN) RBAM_034980(rocA)
BPU: BPUM_0301(ycgN)
OIH: OB1349(rocA)
GKA: GK0187 GK2889
GTN: GTNG_0169
GWC: GWCH70_0274
GYM: GYMC10_0427
GYC: GYMC61_1043
AFL: Aflv_0249(rocA)
SAU: SA2341(rocA)
SAV: SAV2554(rocA)
SAW: SAHV_2538(rocA)
SAM: MW2475(rocA)
SAR: SAR2634
SAS: SAS2440
SAC: SACOL2569
SAB: SAB2428c
SAA: SAUSA300_2491
SAX: USA300HOU_2549
SAO: SAOUHSC_02869
SAJ: SaurJH9_2576
SAH: SaurJH1_2630
SAE: NWMN_2454
SAD: SAAV_2620
SEP: SE2116
SER: SERP2128
SHA: SH0500(rocA)
SSP: SSP0311
SCA: Sca_0564(rocA)
LSP: Bsph_0622
ESI: Exig_2513
EAT: EAT1b_0999
MCL: MCCL_0582
BBE: BBR47_06890(rocA)
PJD: Pjdr2_5338
AAC: Aaci_0323
STH: STH2741 STH646
DRM: Dred_1731
CPO: COPRO5265_1373(pruA)
NTH: Nther_1750
MTU: Rv1187(rocA)
MTC: MT1224(pruA)
MRA: MRA_1197(rocA)
MTF: TBFG_11211
MTB: TBMG_02795(TBMG_02795.1)
MBO: Mb1219(rocA)
MBB: BCG_1249(rocA)
MBT: JTY_1222(rocA)
MPA: MAP2593c(rocA)
MAV: MAV_1331(pruA)
MSM: MSMEG_5119(pruA)
MUL: MUL_0932(rocA)
MVA: Mvan_4526
MGI: Mflv_2172
MAB: MAB_1330
MMC: Mmcs_4026
MKM: Mkms_4101
MJL: Mjls_4256
MMI: MMAR_4253(rocA)
CGL: NCgl0098(cgl0099)
CGB: cg0129(putA)
CGT: cgR_0173
CEF: CE0101
CJK: jk0454(putA)
CUR: cur_1505
CAR: cauri_2326(putA)
CKP: ckrop_0287
NFA: nfa47480
RHA: RHA1_ro00348(rocA1) RHA1_ro05951(rocA2)
RER: RER_47040
ROP: ROP_29500 ROP_60130
GBR: Gbro_1296
SCO: SCO5520(SC1C2.01)
SMA: SAV_2723(rocA)
SGR: SGR_1988
LXX: Lxx02530(poaA)
CMI: CMM_0619(putA)
CMS: CMS_2818
ART: Arth_3884
AAU: AAur_0671
ACH: Achl_3673
RSA: RSal33209_1941
KRH: KRH_01330(putA)
MLU: Mlut_19430
BCV: Bcav_2850
BFA: Bfae_17510
KSE: Ksed_08740
XCE: Xcel_2617
PAC: PPA0620
NCA: Noca_0089 Noca_1220
TFU: Tfu_0433
TCU: Tcur_4016
SRO: Sros_3096
FRA: Francci3_2822
FRE: Franean1_4276
FAL: FRAAL4347(putA)
ACE: Acel_1750
NML: Namu_0202
KRA: Krad_4482
SEN: SACE_1979
SVI: Svir_30800
AMI: Amir_1082 Amir_3077
STP: Strop_0978
SAQ: Sare_0915
CAI: Caci_0647 Caci_7579
RXY: Rxyl_2922
AFO: Afer_1378
PCU: pc0033(putA)
ABA: Acid345_0400
ACA: ACP_2709(pruA)
SUS: Acid_3538
BTH: BT_3115
BFR: BF3796
BVU: BVU_3604
PGI: PG1269(pruA)
PGN: PGN_1401
PDI: BDI_2252
SRU: SRU_1517(pruA)
RMR: Rmar_1231
CHU: CHU_0703
DFE: Dfer_3807
CPI: Cpin_5491
PHE: Phep_0644
GFO: GFO_0395
FJO: Fjoh_1753
FPS: FP0415(pruA)
FBA: FIC_02392
COC: Coch_1569
RBI: RB2501_02650
SMG: SMGWSS_249(putA)
SMS: SMDSEM_260(putA)
OTE: Oter_0715
MIN: Minf_0717
AMU: Amuc_2066
GAU: GAU_3073
RBA: RB8262(putA)
SYN: sll1561(putA)
SYP: SYNPCC7002_A1071(putA)
CYB: CYB_0516
TEL: tlr0416(putA)
MAR: MAE_52300(putA)
CYT: cce_1595(putA)
CYP: PCC8801_0117
CYC: PCC7424_1002
CYH: Cyan8802_0114
GVI: gvip380(putA)
ANA: alr0540
NPU: Npun_F5297
AVA: Ava_2942
TER: Tery_3446
AMR: AM1_C0178(putA)
RRS: RoseRS_1548
RCA: Rcas_2305
CAU: Caur_1794
CAG: Cagg_3333
CHL: Chy400_1941
HAU: Haur_4731
DRA: DR_0813 DR_A0030
DGE: Dgeo_0850 Dgeo_1174
DDR: Deide_13670 Deide_13850
TTH: TTC1213
TTJ: TTHA1578
TLE: Tlet_1448
TME: Tmel_0014
FNO: Fnod_1641
PMO: Pmob_0275
KOL: Kole_1012
TTR: Tter_0870
HLA: Hlac_3373
TAC: Ta0603
TVO: TVN0653
PTO: PTO1261
APE: APE_0807.1
SAI: Saci_0166
SIS: LS215_0436
SIA: M1425_0398
SIM: M1627_0412
SID: M164_0436
SIY: YG5714_0396
SIN: YN1551_2635
MSE: Msed_0367
 |
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| Structures |
PDB: 2BHP 2BHQ 2BJA 2BJK 2EHQ 2EHU 2EII 2EIT 2EIW 2EJ6
2EJD 2EJL 2IY6 2J40 2J5N 3ITG |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13681370]
ADAMS E, GOLDSTONE A.
Hydroxyproline metabolism. IV. Enzymatic synthesis of
gamma-hydroxyglutamate from Delta
1-pyrroline-3-hydroxy-5-carboxylate.
J. Biol. Chem. 235 (1960) 3504-12.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
|
2
Strecker, H.J.
The interconversion of glutamic acid and proline. III.
Delta1-Pyrroline-5-carboxylic acid dehydrogenase.
J. Biol. Chem. 235 (1960) 3218-3223. |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:12223682]
Forlani G, Scainelli D, Nielsen E.
[delta]1-Pyrroline-5-Carboxylate Dehydrogenase from Cultured Cells
of Potato (Purification and Properties).
Plant. Physiol. 113 (1997) 1413-1418.
Solanum tuberosum |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:1618807]
Brown ED, Wood JM.
Redesigned purification yields a fully functional PutA protein dimer
from Escherichia coli.
J. Biol. Chem. 267 (1992) 13086-92.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:17554163]
Inagaki E, Ohshima N, Sakamoto K, Babayeva ND, Kato H, Yokoyama S,
Tahirov TH.
New insights into the binding mode of coenzymes: structure of
Thermus thermophilus Delta1-pyrroline-5-carboxylate dehydrogenase
complexed with NADP+.
Acta. Crystallogr. Sect. F. Struct. Biol. Cryst. Commun. 63 (2007)
462-5.
Thermus thermophilus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.5.1.12
IUBMB Enzyme Nomenclature: 1.5.1.12
ExPASy - ENZYME nomenclature database: 1.5.1.12
BRENDA, the Enzyme Database: 1.5.1.12
CAS: 9054-82-4 |
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