| Entry |
|
|---|
| Name |
D-lysopine dehydrogenase;
D-lysopine synthase;
lysopine dehydrogenase;
D(+)-lysopine dehydrogenase;
2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase
(L-lysine-forming) |
|---|
| Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase
(L-lysine-forming) |
|---|
| Reaction(IUBMB) |
N2-(D-1-carboxyethyl)-L-lysine + NADP+ + H2O = L-lysine + pyruvate +
NADPH + H+ [RN:R00452] |
|---|
| Reaction(KEGG) |
R00452
 |
|---|
| Substrate |
N2-(D-1-carboxyethyl)-L-lysine [CPD:C04020];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Product |
L-lysine [CPD:C00047];
pyruvate [CPD:C00022];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
In the reverse reaction, a number of L-amino acids can act instead
of L-lysine, and 2-oxobutanoate and, to a lesser extent, glyoxylate
can act instead of pyruvate. |
|---|
| Pathway |
PATH: ec00310 Lysine degradation |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:21695]
Otten LA, Vreugdenhil D, Schilperoort RA.
Properties of D(+)-lysopine dehydrogenase from crown gall tumour
tissue.
Biochim. Biophys. Acta. 485 (1977) 268-77.
Nicotiana tabacum |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.5.1.16
IUBMB Enzyme Nomenclature: 1.5.1.16
ExPASy - ENZYME nomenclature database: 1.5.1.16
BRENDA, the Enzyme Database: 1.5.1.16
CAS: 65187-41-9 |
|---|
